The greater Philadelphia metropolitan area, including Horsham, Bryn Mawr, Wayne, Eddystone, and the Main Line suburbs, supports one of the most medically distinguished regenerative medicine markets in the country, anchored by the University of Pennsylvania Health System, Rothman Orthopaedics, and a strong tradition of professional sports medicine serving the Eagles, 76ers, Flyers, and Phillies. The region’s providers include the founding director of the Penn Regenerative Sports Medicine and Orthobiologics Program, two certified Regenexx network physicians, a high-volume independent practice performing approximately 4,000 procedures annually, and a quadruple board-certified physiatrist who is also a recognized Regenexx provider. The providers listed below represent established practices with verified addresses, documented treatment offerings, and publicly available contact information.
This directory is for informational purposes only. It does not constitute medical advice, endorsement, or recommendation. Inclusion in this directory does not imply certification or quality rating. Always consult a qualified healthcare provider before pursuing any treatment.
Quick Guide by Condition
If you are looking for a provider based on your specific concern, this overview may help narrow your search:
University-based regenerative sports medicine with professional team credentials: The Penn Regenerative Sports Medicine and Orthobiologics Program, led by Dr. Arsh Dhanota at Penn Medicine, is the region’s only academic medical center program dedicated exclusively to orthobiologic treatment. Dr. Dhanota serves as Chief Medical Officer and Head Team Physician for the Philadelphia Eagles and Head Primary Care Sports Medicine Physician for the Philadelphia 76ers.
Regenexx bone marrow concentrate and interventional pain: Regenexx Philadelphia (Dr. Sanjay Shah, Horsham) and the Regenerative Joint and Spine Center at Premier Orthopaedics (Dr. Jeffrey Berger, Wayne) are both certified Regenexx network providers offering proprietary bone marrow concentrate and platelet protocols under advanced image guidance across southeastern Pennsylvania.
High-volume independent practice with professional athlete experience: Greenberg Regenerative Medicine in Bryn Mawr, led by Dr. Scott Greenberg, performs approximately 4,000 procedures annually and has treated athletes from the Philadelphia Eagles, Flyers, Phillies, and 76ers. Dr. Greenberg chairs the Institutional Review Board of the American Association of Stem Cell Physicians and was a member of the first team to publish a case study repairing a meniscus tear using autologous stem cell therapy.
1. Penn Regenerative Sports Medicine and Orthobiologics Program
The Penn Regenerative Sports Medicine and Orthobiologics Program at Penn Medicine is led by Dr. Arsh S. Dhanota, the program’s founding director, an Associate Professor at the Perelman School of Medicine at the University of Pennsylvania, and the Chief Medical Officer and Head Team Physician for the Philadelphia Eagles. Dr. Dhanota earned his bachelor’s degree in Electrical Engineering from the University of California, Riverside, and his medical degree from the Medical University of Lublin with two years of clinical training at the hospitals of Weill Medical College at Cornell University (2009). He completed his family medicine residency at the David Geffen School of Medicine UCLA and Kaiser Foundation Hospital program in Southern California, where he served as elected Chief Resident and received the Resident Research Award for sports medicine research. He then completed a fellowship in Adult and Pediatric Sports Medicine at the Children’s Hospital of Philadelphia and University of Pennsylvania Sports Medicine Fellowship. He is board-certified by the American Board of Family Medicine with subspecialty certification in Sports Medicine (CAQSM). In addition to his role with the Eagles, he serves as Head Primary Care Sports Medicine Physician for the Philadelphia 76ers and has previously served as team physician for the Philadelphia Flyers. He is Founding Chief of the Division of Primary Care Sports Medicine at Penn Medicine and has developed advanced cell-based treatment protocols for musculoskeletal injuries through the Penn Institute for Regenerative Medicine.
Address: 235 South 33rd Street, Weightman Hall, 1st Floor, Philadelphia, PA 19104
Phone: (215) 316-5151
Key Personnel:
- Dr. Arsh S. Dhanota, MD, CAQSM, Founding Director, board-certified in Family Medicine with Sports Medicine subspecialty, Medical University of Lublin and Weill Cornell MD (2009), UCLA-Kaiser family medicine residency (Chief Resident), CHOP and Penn Sports Medicine fellowship, CMO and Head Team Physician Philadelphia Eagles, Head Primary Care Sports Medicine Physician Philadelphia 76ers
Services Offered:
- Platelet-Rich Plasma (PRP) therapy
- Orthobiologic treatments for musculoskeletal conditions
- Tenex minimally invasive tendinopathy treatment
- Sports medicine consultation and evaluation
- Cell-based treatment protocols for sports and activity-related injuries
Conditions Treated: Tendinopathies, sports injuries, musculoskeletal pain, ligament and tendon conditions, joint conditions in athletes and active patients
Hours: Monday through Friday, 8:00 AM to 5:00 PM
2. Regenexx Philadelphia
Regenexx Philadelphia is a Horsham practice led by Dr. Sanjay M. Shah, a dual board-certified anesthesiologist and pain medicine specialist who founded Regenexx Philadelphia in 2014. Dr. Shah earned his undergraduate degree from Johns Hopkins University and his medical degree from Ponce Health Sciences University in Puerto Rico. He completed both his anesthesiology residency and fellowship in Pain Management at Thomas Jefferson University Hospital in Philadelphia, training at one of the region’s most prominent academic medical centers. He holds dual board certification in Anesthesiology and Pain Medicine (subspecialty certification) from the American Board of Anesthesiology and has 24 years of clinical experience in pain management and interventional procedures. As a certified Regenexx network provider, Dr. Shah applies Regenexx proprietary bone marrow concentrate and super-concentrated platelet protocols under advanced image guidance for joint, tendon, and spine conditions. He also practices at SEPA Pain and Spine in Horsham and Langhorne.
Address: 508 Prudential Road, Horsham, PA 19044
Phone: (215) 867-6896
Website: https://regenexxphiladelphia.com
Key Personnel:
- Dr. Sanjay M. Shah, MD, Lead Physician and Founder, dual board-certified in Anesthesiology and Pain Medicine, Johns Hopkins University undergraduate, Ponce Health Sciences University MD, Thomas Jefferson University Hospital anesthesiology residency and Pain Management fellowship, certified Regenexx network provider since 2014
Services Offered:
- Bone marrow aspirate concentrate (Regenexx SD and related protocols)
- Super-concentrated platelet therapy (Regenexx SCP protocol)
- Image-guided joint and spine injection procedures
- Interventional pain management
- Non-surgical orthobiologic treatment
Conditions Treated: Knee and hip arthritis, shoulder and rotator cuff conditions, spine and disc conditions, tendon and ligament injuries, sports injuries, musculoskeletal pain conditions
3. Greenberg Regenerative Medicine
Greenberg Regenerative Medicine in Bryn Mawr is a high-volume independent practice led by Dr. Scott R. Greenberg, a board-certified family medicine physician who founded the practice in 2019 and performs approximately 4,000 regenerative procedures annually. Dr. Greenberg earned his medical degree from Hahnemann University College of Medicine (now Drexel University College of Medicine) in 1996 and completed his family medicine residency at Bryn Mawr Hospital on the Philadelphia Main Line. He is board-certified in Family Practice and is a diplomate of the National Board of Medical Examiners. He serves as Director of the Regenerative Medicine Team at the Dee Adams Center for Integrative and Regenerative Medicine at Bryn Mawr Hospital and as Clinical Professor at the Marcus Institute of Integrative Medicine at Thomas Jefferson University Hospital. He chairs the Institutional Review Board of the American Association of Stem Cell Physicians, is a founding board member of that organization, and was a member of the first team to publish a case study repairing a meniscus tear using autologous stem cell therapy. He has treated athletes from the Philadelphia Eagles, Philadelphia Flyers, Philadelphia Phillies, Philadelphia 76ers, Baltimore Ravens, San Francisco 49ers, New England Patriots, and Toronto Blue Jays.
Address: 101 S Bryn Mawr Avenue, Suite 300a, Bryn Mawr, PA 19010
Phone: (833) 440-4325
Website: https://greenbergregen.com
Key Personnel:
- Dr. Scott R. Greenberg, MD, Founder, board-certified in Family Practice, Hahnemann University College of Medicine MD (1996), Bryn Mawr Hospital family medicine residency, Clinical Professor Marcus Institute of Integrative Medicine at Thomas Jefferson University, chair IRB American Association of Stem Cell Physicians
Services Offered:
- Stem cell therapy (autologous)
- Platelet-Rich Plasma (PRP) therapy
- Prolotherapy
- Osteopathic manipulative treatment
Conditions Treated: Orthopedic injuries, osteoarthritis, tendon and ligament conditions, spine conditions, sports injuries, post-concussion syndrome (as reported by the provider)
Hours: Monday through Friday, 9:00 AM to 5:00 PM
4. Regenerative Joint and Spine Center at Premier Orthopaedics
The Regenerative Joint and Spine Center at Premier Orthopaedics in Wayne is led by Dr. Jeffrey S. Berger, a quadruple board-certified physiatrist and interventional pain specialist who is also a certified Regenexx network provider. Dr. Berger earned his DO degree from Philadelphia College of Osteopathic Medicine and completed his Physical Medicine and Rehabilitation residency at Temple University Hospital and Moss Rehabilitation, where he served as Chief Resident and received the James A. Demopoulos Resident of the Year Award. He then completed a fellowship in Interventional Pain Medicine at Temple University and served as Clinical Instructor there. He holds board certification in Physical Medicine and Rehabilitation, Pain Medicine, Sports Medicine, and Electrodiagnostic Medicine. He has pursued additional training in regenerative medicine, orthobiologics, musculoskeletal ultrasound, and neurostimulation, and has authored award-winning research articles and book chapters. He has been recognized as a Philadelphia Magazine and Main Line Today Top Doctor. As a Regenexx-certified provider, he offers the full suite of Regenexx proprietary bone marrow concentrate and platelet protocols alongside interventional pain and spine procedures.
Address: 676 E. Swedesford Road, Suite 170, Wayne, PA 19087
Phone: (484) 685-1957
Website: https://regenerativejointandspine.com
Key Personnel:
- Dr. Jeffrey S. Berger, DO, Lead Physician, quadruple board-certified in Physical Medicine and Rehabilitation, Pain Medicine, Sports Medicine, and Electrodiagnostic Medicine, Philadelphia College of Osteopathic Medicine DO, Temple University PM&R residency (Chief Resident, Resident of the Year), Temple University Interventional Pain Medicine fellowship, certified Regenexx network provider
Services Offered:
- Bone marrow aspirate concentrate (Regenexx protocols)
- Platelet-Rich Plasma (PRP) therapy (Regenexx protocols)
- Interventional spine procedures
- Musculoskeletal ultrasound-guided injections
- Neurostimulation (as indicated)
- Advanced orthobiologic treatments
Conditions Treated: Spine and disc conditions, joint arthritis and pain, tendon and ligament injuries, musculoskeletal pain, sports injuries, complex spine and pain conditions
Hours: Monday through Friday, 8:00 AM to 5:00 PM
5. Philadelphia PRP and Stem Cell Institute
The Philadelphia PRP and Stem Cell Institute in Eddystone is led by Dr. Bruce Grossinger, a board-certified neurologist and pain medicine specialist who applies a neurology and electrodiagnostic background to orthobiologic treatment for musculoskeletal and spine conditions. Dr. Grossinger holds board certification in Neurology, Pain Medicine (ABPN subsection and AAPM Diplomate), and Electrodiagnostic Medicine, and is credentialed as an Independent Medical Evaluator. The practice specializes in non-surgical pain relief and orthobiologic therapies, including PRP and bone marrow-derived cell procedures, for patients seeking alternatives to surgery or long-term medication use. The practice serves southeastern Pennsylvania and northern Delaware from its Eddystone location, with an additional office in Wilmington, Delaware.
Address: 1510 Chester Pike, Suite 130, Eddystone, PA 19022
Phone: (610) 521-6063
Website: https://phillysportsdoc.com
Key Personnel:
- Dr. Bruce Grossinger, MD, Lead Physician, board-certified in Neurology, Pain Medicine, and Electrodiagnostic Medicine, Independent Medical Evaluator
Services Offered:
- Platelet-Rich Plasma (PRP) therapy
- Bone marrow-derived cell procedures
- Non-surgical pain management
- Sports medicine consultation
Conditions Treated: Musculoskeletal pain, joint conditions, tendon and ligament injuries, spine conditions, sports injuries, chronic pain conditions
Hours: Monday through Friday, 9:00 AM to 5:00 PM
About This Directory
This listing is part of a national regenerative medicine directory covering major metropolitan areas across the United States. Clinics included in this directory are real, operating practices with verified addresses and publicly available contact information. Inclusion does not imply endorsement, certification, or quality rating. Patients should independently verify provider credentials, treatment protocols, and regulatory compliance before pursuing any regenerative medicine treatment.
Many regenerative medicine treatments, including stem cell therapy and PRP, are considered investigational by the FDA for most orthopedic and musculoskeletal applications. Insurance coverage for these treatments is generally not available. Patients are encouraged to discuss all treatment options, risks, benefits, and costs with their healthcare provider before making any decisions.
Last updated: March 2026