The greater Raleigh metropolitan area, including Cary, Morrisville, Wake Forest, and surrounding Wake County communities, supports a competitive regenerative medicine market built on a foundation of Research Triangle academic medicine, proximity to Duke University Health and WakeMed sports medicine programs, and deep orthopedic expertise serving the Carolina Hurricanes and NC State athletic programs. Raleigh-area providers include a Duke Sports Medicine-fellowship-trained osteopathic physician who has performed more than 50,000 ultrasound-guided procedures, a fellowship-trained orthopedic surgeon who serves as team physician for the Carolina Hurricanes NHL franchise and was the first physician in Wake County to perform the MACI cartilage restoration procedure, a University of Virginia-trained physiatrist and US Army veteran who became the first Regenexx-certified provider in North Carolina, and a multi-physician interventional pain and regenerative medicine practice whose co-founders hold double board certification in Physical Medicine and Rehabilitation and Pain Medicine. The providers listed below represent established practices with verified addresses, documented treatment offerings, and publicly available contact information.
This directory is for informational purposes only. It does not constitute medical advice, endorsement, or recommendation. Inclusion in this directory does not imply certification or quality rating. Always consult a qualified healthcare provider before pursuing any treatment.
Quick Guide by Condition
If you are looking for a provider based on your specific concern, this overview may help narrow your search:
Non-surgical sports medicine with fellowship training and ultrasound-guided injection expertise: Dr. Matthew Kanaan at Carolina Nonsurgical Orthopedics (Lake Erie College of Osteopathic Medicine DO, Duke Medical Center residency, Duke Sports Medicine Nonsurgical Sports Medicine fellowship, 50,000+ ultrasound-guided procedures) and Dr. Chad Greer at WakeMed Wake Orthopaedics (Brody School of Medicine at ECU MD, VCU Health System Internal Medicine and Pediatrics residency, AnMed Health Sports Medicine fellowship, first non-operative sports medicine physician in Triangle orthopedic setting) offer nonsurgical and minimally invasive regenerative treatment options across the Raleigh metro area.
Fellowship-trained orthopedic surgery with professional team medicine credentials and regenerative options: Dr. Joseph U. Barker at Raleigh Orthopaedic Clinic (Duke University School of Medicine MD, Cornell University and Hospital for Special Surgery orthopedic residency, Rush University Medical Center sports medicine fellowship, team physician Carolina Hurricanes NHL and NC State University Athletics) offers PRP, BMAC, and the MACI cartilage restoration procedure alongside a full range of orthopedic surgical services for patients in the Triangle area.
Regenexx-certified interventional orthobiologics and pain medicine: Dr. Dwayne Patterson at Interventional Orthopedics of Raleigh (University of Virginia MD, Walter Reed Army Medical Center PM&R residency, first Regenexx-certified provider in North Carolina) and Spine and Pain Associates (Dr. Jasbir Dhaliwal: Ross University School of Medicine MD, SUNY Upstate PM&R residency and Pain Medicine fellowship, double board-certified; Dr. Krishna Bhat: American University of the Caribbean MD, Rush University Medical Center PM&R residency, Regenexx network) offer image-guided regenerative orthobiologic treatment for joint, tendon, and spine conditions.
1. Carolina Nonsurgical Orthopedics
Carolina Nonsurgical Orthopedics in Raleigh is the practice of Dr. Matthew Kanaan, a fellowship-trained osteopathic physician who founded the practice after completing his sports medicine training at Duke and has dedicated his career to nonsurgical orthopedic treatment and ultrasound-guided regenerative procedures. Dr. Kanaan earned his Bachelor of Science in Clinical Psychology from Liberty University and a Master of Science in Clinical Psychology from the University of Central Florida. He earned his Doctor of Osteopathic Medicine from Lake Erie College of Osteopathic Medicine in 2009. He completed a General Medicine residency at Duke Medical Center from 2009 to 2012 and then completed a fellowship in Nonsurgical Sports Medicine at Duke Sports Medicine from 2012 to 2013, where he developed specialized expertise in diagnostic and therapeutic musculoskeletal ultrasound. He is board-certified in Family Medicine and Sports Medicine by the American Board of Family Medicine. He served as an assistant team physician at Duke University and Elon University following his fellowship training. He is Founder and Medical Director of Carolina Nonsurgical Orthopedics and has performed more than 50,000 ultrasound-guided procedures during his career, specializing in cell therapy, platelet-rich plasma, prolotherapy, and advanced image-guided joint and tendon treatment for patients seeking nonsurgical solutions.
Address: 7200 Creedmoor Road, Suite 102, Raleigh, NC 27613
Phone: (919) 719-2270
Website: https://www.carolinanonsurgicalortho.com
Key Personnel:
- Dr. Matthew Kanaan, DO, Founder and Medical Director, board-certified in Family Medicine and Sports Medicine (ABFM), Lake Erie College of Osteopathic Medicine DO (2009), Duke Medical Center General Medicine residency (2009-2012), Duke Sports Medicine Nonsurgical Sports Medicine fellowship (2012-2013), former assistant team physician Duke University and Elon University, 50,000+ ultrasound-guided procedures
Services Offered:
- Platelet-Rich Plasma (PRP) therapy
- Cell therapy and orthobiologic injection procedures
- Prolotherapy
- Shockwave therapy
- Ultrasound-guided musculoskeletal injection procedures
- Diagnostic musculoskeletal ultrasound
Conditions Treated: Knee, hip, shoulder, and ankle osteoarthritis, tendinopathies, ligament injuries, rotator cuff conditions, plantar fasciitis, sports injuries, overuse injuries, musculoskeletal pain in patients seeking nonsurgical and minimally invasive care
2. Raleigh Orthopaedic Clinic
Raleigh Orthopaedic Clinic is one of the Triangle’s largest and most established orthopedic groups, with its sports medicine and regenerative medicine program led by Dr. Joseph U. Barker, a board-certified orthopedic surgeon and sports medicine specialist who serves as team physician for the Carolina Hurricanes NHL franchise and NC State University Athletics. Dr. Barker earned his undergraduate degree from Wake Forest University with a 4.0 grade point average and his medical degree from Duke University School of Medicine, where he was awarded the Howard Hughes Medical Institute fellowship for orthopedic research. He completed his surgical internship at New York Hospital/Cornell University and his orthopedic surgery residency at Cornell University in affiliation with the Hospital for Special Surgery in New York, ranked the number one orthopedic hospital in the United States. He then completed a fellowship in Sports Medicine at Rush University Medical Center in Chicago, during which he served as assistant team physician for the DePaul University Blue Demons, the Chicago Steel Hockey Club, the Chicago White Sox, and the Chicago Bulls. He is board-certified by the American Board of Orthopaedic Surgery with a Subspecialty Certificate in Orthopaedic Sports Medicine (2014). He has authored or co-authored more than 20 peer-reviewed publications and book chapters and was the first physician in Wake County to perform the MACI (Matrix Associated Chondrocyte Implantation) cartilage restoration procedure. The practice also includes Dr. Matthew Kippe, a fellowship-trained physiatrist who leads the interventional orthopaedics program at Raleigh Orthopaedic.
Address: 3001 Edwards Mill Road, Raleigh, NC 27612
Phone: (919) 781-5600
Website: https://www.raleighortho.com
Key Personnel:
- Dr. Joseph U. Barker, MD, Sports Medicine Lead, dual board-certified in Orthopaedic Surgery and Orthopaedic Sports Medicine (2014), Wake Forest University BS (4.0 GPA), Duke University School of Medicine MD (Howard Hughes Medical Institute fellowship), Cornell University/Hospital for Special Surgery orthopedic surgery residency, Rush University Medical Center sports medicine fellowship, team physician Carolina Hurricanes NHL, NC State University Athletics, first physician in Wake County to perform MACI procedure
Services Offered:
- Platelet-Rich Plasma (PRP) therapy
- Bone Marrow Aspirate Concentrate (BMAC) therapy
- MACI (Matrix Associated Chondrocyte Implantation) cartilage restoration
- Arthroscopic knee, shoulder, and hip surgery (when indicated)
- ACL reconstruction and complex ligament repair
- Sports medicine consultation and management
Conditions Treated: Knee cartilage injuries, ACL and ligament tears, meniscal conditions, shoulder instability and rotator cuff conditions, hip labral tears, osteoarthritis, sports injuries at the high school, collegiate, professional, and recreational level
3. WakeMed Wake Orthopaedics
WakeMed Wake Orthopaedics is the orthopedic sports medicine and interventional orthopaedics program of WakeMed Health and Hospitals, serving patients across the Raleigh metropolitan area. The interventional orthopaedics and regenerative medicine program is led by Dr. Chad Greer, a board-certified sports medicine physician who was the first non-operative sports medicine physician to practice within a Triangle orthopedic surgery setting. Dr. Greer earned his medical degree from the Brody School of Medicine at East Carolina University in 2005. He completed a combined residency in Internal Medicine and Pediatrics at the VCU Health System from 2005 to 2009 and then completed a fellowship in Sports Medicine at AnMed Health in Anderson, South Carolina in 2010. He is board-certified in both Internal Medicine and Sports Medicine. He joined WakeMed Wake Orthopaedics and established its dedicated non-operative sports medicine and interventional orthopaedics presence, offering PRP, BMAC, alpha-2 macroglobulin (A2M) protein concentrate, and diagnostic musculoskeletal ultrasound within the WakeMed orthopedic group. The fellowship-trained team at Wake Orthopaedics uses ultrasound guidance for precision delivery of orthobiologic injections.
Address: 10010 Falls of Neuse Road, Suite 011, Raleigh, NC 27614
Phone: (919) 714-6184
Website: https://www.wakemed.org/wakemed-wake-orthopaedics
Key Personnel:
- Dr. Chad Greer, MD, Sports Medicine and Interventional Orthopaedics Lead, board-certified in Internal Medicine and Sports Medicine, Brody School of Medicine at East Carolina University MD (2005), VCU Health System Internal Medicine and Pediatrics residency (2005-2009), AnMed Health Sports Medicine fellowship (2010)
Services Offered:
- Platelet-Rich Plasma (PRP) therapy
- Bone Marrow Aspirate Concentrate (BMAC) therapy
- Alpha-2 Macroglobulin (A2M) protein concentrate injections
- Ultrasound-guided musculoskeletal injection procedures
- Non-operative sports medicine evaluation and management
- Diagnostic musculoskeletal ultrasound
Conditions Treated: Osteoarthritis of the knee, hip, and shoulder, tendon and ligament injuries, sports injuries, overuse conditions, joint pain, musculoskeletal conditions in athletes and active patients seeking non-surgical treatment
4. Interventional Orthopedics of Raleigh
Interventional Orthopedics of Raleigh is the practice of Dr. Dwayne E. Patterson, a board-certified physiatrist, US Army veteran, and the first Regenexx-certified provider in North Carolina. Dr. Patterson earned both his undergraduate degree in Biology and his medical degree from the University of Virginia, completing his bachelor’s degree in 1985 and his Doctor of Medicine in 1989. He entered the US Army and completed his residency in Physical Medicine and Rehabilitation at Walter Reed Army Medical Center, where he won the Resident Research Award and achieved the rank of Major. He has been practicing in Raleigh since 1997, joining a local orthopedic group where his clinical focus centered on non-surgical treatment of orthopedic conditions, injection therapy, and rehabilitation of spine and sports injuries. After many years of practice, his interest in advancing regenerative orthopedic care led him to complete extensive training in advanced interventional injection techniques at the Regenexx Centeno-Schultz Clinic and to become certified by the Interventional Orthobiologics Foundation. He is a Fellow of the American Academy of Physical Medicine and Rehabilitation and a member of the Interventional Orthobiologics Foundation. He is Founder and Medical Director of Interventional Orthopedics of Raleigh, established as a dedicated regenerative orthopedic practice offering Regenexx proprietary bone marrow concentrate and platelet protocols under advanced image guidance.
Address: 7101 Creedmoor Road, Suite 109, Raleigh, NC 27613
Phone: (919) 324-1704
Website: https://ioraleigh.com
Key Personnel:
- Dr. Dwayne E. Patterson, MD, Founder and Medical Director, board-certified in Physical Medicine and Rehabilitation, FAAPMR, University of Virginia BA Biology (1985) and MD (1989), Walter Reed Army Medical Center PM&R residency (Resident Research Award, rank of Major), first Regenexx-certified provider in North Carolina, IOF-certified, US Army veteran
Services Offered:
- Bone marrow aspirate concentrate (Regenexx protocols)
- Platelet-Rich Plasma (PRP) therapy (Regenexx protocols)
- Image-guided joint and spine injection procedures
- Non-surgical orthopedic evaluation and management
- Regenerative treatment for spine, joint, and tendon conditions
Conditions Treated: Cervical, thoracic, and lumbar spine conditions, knee and hip osteoarthritis, shoulder conditions, elbow, wrist, hand, foot, and ankle conditions, tendon and ligament injuries, sports injuries, musculoskeletal pain in patients seeking non-surgical regenerative care
5. Spine and Pain Associates
Spine and Pain Associates is a multi-physician interventional pain management and regenerative medicine practice co-founded by Dr. Jasbir Dhaliwal and Dr. Krishna Bhat, both of whom are Regenexx-affiliated providers offering image-guided orthobiologic injection therapies alongside interventional spine and pain management care. The practice serves patients across the Triangle region from its Raleigh location. Dr. Dhaliwal earned his undergraduate degree in Biological Sciences and Biochemical Pharmacology from the State University of New York at Buffalo and his medical degree from Ross University School of Medicine. He completed a General Surgery internship at Albert Einstein College of Medicine in the Bronx, New York, and then completed his residency in Physical Medicine and Rehabilitation at SUNY Upstate Medical University in Syracuse, where he served as Chief Resident. He then completed a one-year ACGME-accredited fellowship in Pain Medicine through the Department of Anesthesiology at SUNY Upstate Medical University, gaining advanced expertise in interventional spine care, neuromodulation, and fluoroscopic and ultrasound-guided procedures. He is double board-certified in Physical Medicine and Rehabilitation and Pain Medicine and is a member of the Interventional Orthobiologics Foundation. Dr. Bhat earned his medical degree from the American University of the Caribbean in 2001 and completed his Physical Medicine and Rehabilitation residency at Rush University Medical Center in Chicago, where he served as Chief Resident. He has been practicing in the Raleigh area since 2012 and is board-certified in Physical Medicine and Rehabilitation. Both physicians are Regenexx network-affiliated providers.
Address: 3840 Ed Drive, Suite 111, Raleigh, NC 27612
Phone: (919) 825-3902
Website: https://spineandpainassociates.com
Key Personnel:
- Dr. Jasbir Dhaliwal, MD, Co-Founder, double board-certified in Physical Medicine and Rehabilitation and Pain Medicine, SUNY Buffalo BS, Ross University School of Medicine MD, Albert Einstein College of Medicine General Surgery internship, SUNY Upstate Medical University PM&R residency (Chief Resident), SUNY Upstate ACGME Pain Medicine fellowship, Regenexx-affiliated provider, IOF member
- Dr. Krishna Bhat, MD, Co-Founder, board-certified in Physical Medicine and Rehabilitation, American University of the Caribbean MD (2001), Rush University Medical Center PM&R residency (Chief Resident), Regenexx network provider, in practice in Raleigh since 2012
Services Offered:
- Bone marrow aspirate concentrate (Regenexx protocols)
- Platelet-Rich Plasma (PRP) therapy
- Interventional spine procedures (epidural, facet, sacroiliac joint injections)
- Fluoroscopic and ultrasound-guided injection procedures
- Neuromodulation and spinal cord stimulation
- Comprehensive pain management consultation
Conditions Treated: Spine and disc conditions, back and neck pain, joint osteoarthritis, tendon and ligament injuries, chronic musculoskeletal pain, neuropathic pain, sports injuries in patients seeking minimally invasive or regenerative treatment
About This Directory
This listing is part of a national regenerative medicine directory covering major metropolitan areas across the United States. Clinics included in this directory are real, operating practices with verified addresses and publicly available contact information. Inclusion does not imply endorsement, certification, or quality rating. Patients should independently verify provider credentials, treatment protocols, and regulatory compliance before pursuing any regenerative medicine treatment.
Many regenerative medicine treatments, including stem cell therapy and PRP, are considered investigational by the FDA for most orthopedic and musculoskeletal applications. Insurance coverage for these treatments is generally not available. Patients are encouraged to discuss all treatment options, risks, benefits, and costs with their healthcare provider before making any decisions.
Last updated: March 2026