The Denver metropolitan area holds a unique place in the national regenerative medicine landscape as the home of the Centeno-Schultz Clinic, the world headquarters of the Regenexx network, where orthopedic stem cell injection procedures were first developed in 2005. The region supports a broad concentration of board-certified orthopedic surgeons, sports medicine specialists, and pain management physicians offering autologous bone marrow concentrate, platelet-rich plasma, adipose-derived cell therapies, and prolotherapy across Denver, Broomfield, Centennial, Englewood, and Boulder. Patients in Greater Denver have access to providers ranging from nationally recognized Regenexx founders to team physicians for the Denver Broncos and Colorado Rockies. The providers listed below represent established practices with verified addresses, documented treatment offerings, and publicly available contact information.
This directory is for informational purposes only. It does not constitute medical advice, endorsement, or recommendation. Inclusion in this directory does not imply certification or quality rating. Always consult a qualified healthcare provider before pursuing any treatment.
Quick Guide by Condition
If you are looking for a provider based on your specific concern, this overview may help narrow your search:
Orthopedic and joint conditions (knee, hip, shoulder, spine): Centeno-Schultz Clinic, Denver Sports Ortho, Mountain Spine and Pain Physicians, and Boulder Biologics all specialize in orthopedic biologic therapies. Dr. Braden Mayer at Denver Sports Ortho serves as team physician for the Denver Broncos.
Bone marrow concentrate and Regenexx protocols: Centeno-Schultz Clinic is the world headquarters of the Regenexx network and was the first clinic in the world to develop bone marrow concentrate procedures for orthopedic conditions. thriveMD also offers bone marrow and PRP combination protocols for joint and spine conditions.
Wellness and hormone optimization alongside regenerative orthopedics: Denver Regenerative Medicine has served the Denver area since 2010 and offers the acCELLerate™ combination protocol alongside hormone therapies for patients seeking a broader integrative approach.
1. Centeno-Schultz Clinic
The Centeno-Schultz Clinic is the world headquarters of the international Regenexx network and the clinic where Regenexx bone marrow concentrate and platelet-rich plasma procedures were invented. In 2005, Dr. Christopher J. Centeno and Dr. John R. Schultz became the first physicians in the world to apply bone marrow concentrate to treat orthopedic injuries using a highly specific, image-guided injection approach. The clinic maintains a university-level clinical and lab research facility and reinvests a portion of annual revenue into ongoing research and development. The practice has published dozens of peer-reviewed articles on orthopedic regenerative medicine and maintains detailed outcome data across its patient population.
Address: 403 Summit Boulevard, Suite 201, Broomfield, CO 80021
Phone: (303) 429-6448
Website: https://centenoschultz.com
Key Personnel:
- Dr. Christopher J. Centeno, MD, Co-Founder, international expert in Interventional Orthopedics and bone marrow concentrate, trained at Baylor College of Medicine and the Institute for Rehabilitation Research
- Dr. John R. Schultz, MD, Co-Founder and Co-Medical Director, double board-certified in Anesthesiology and Pain Management, former instructor for the Spine Intervention Society
Services Offered:
- Bone marrow concentrate (Regenexx protocol) procedures
- Platelet-Rich Plasma (PRP) and platelet lysate injections
- Image-guided orthopedic injections
- Non-surgical treatment for joint, spine, and soft tissue conditions
Conditions Treated: Knee and hip arthritis, tendon and ligament injuries, spine and disc conditions, shoulder injuries, sports-related musculoskeletal conditions, degenerative joint disease
Hours: Monday through Friday, 7:00 AM to 5:00 PM
2. thriveMD
thriveMD is a Colorado regenerative medicine clinic with locations in Centennial and Vail, led by Dr. Scott Brandt, Medical Director. Dr. Brandt is among a select group of physicians in the country trained in advanced bone marrow concentrate procedures and has been featured in the Denver Post and on FOX television discussing stem cell treatments as alternatives to knee replacement, hip replacement, and spinal fusion surgeries. The clinic harvests bone marrow from the patient’s iliac crest under live X-ray guidance and concentrates the cells using a centrifuge for same-day injection into affected joints or spinal structures. Platelet-Rich Plasma is derived from a peripheral blood draw and can be combined with bone marrow concentrate for joint, soft tissue, and back pain conditions.
Address: 7400 East Caley Avenue, Suite 150, Centennial, CO 80111
Phone: (720) 575-7878
Website: https://thrivemdclinic.com
Key Personnel:
- Dr. Scott Brandt, MD, Medical Director, specialist in regenerative medicine, stem cell therapy, and non-surgical orthopedics
Services Offered:
- Bone marrow concentrate stem cell therapy
- Platelet-Rich Plasma (PRP) therapy
- Combination bone marrow and PRP protocols
- Non-surgical knee, hip, and spine treatments
Conditions Treated: Knee pain and osteoarthritis, hip pain, low back conditions, disc degeneration, shoulder injuries, sports injuries, soft tissue damage, degenerative joint disease
Hours: Monday through Friday, 8:30 AM to 5:00 PM
3. Mountain Spine and Pain Physicians
Mountain Spine and Pain Physicians is a Denver practice led by Dr. Brian J. Fuller, a physician triple board-certified in Physical Medicine and Rehabilitation, Electrodiagnostic Medicine, and Pain Medicine. Dr. Fuller completed a Pain Medicine fellowship at Harvard’s Brigham and Women’s Hospital and a residency in Physical Medicine and Rehabilitation at the University of Michigan. He is an associate professor at Rocky Vista University College of Osteopathic Medicine, has been awarded a National Institute of Disability and Rehabilitation Research grant, and has published original research in premier spine and rehabilitation medicine journals. The practice offers stem cell therapy as a minimally invasive treatment for spine and musculoskeletal pain conditions.
Address: 2373 Central Park Boulevard, Suite 303, Denver, CO 80238
Phone: (303) 355-3700
Website: https://www.mountain-spine.com
Key Personnel:
- Dr. Brian J. Fuller, MD, Founder, triple board-certified in Physical Medicine and Rehabilitation, Electrodiagnostic Medicine, and Pain Medicine; Harvard fellowship at Brigham and Women’s Hospital; associate professor at Rocky Vista University
Services Offered:
- Stem cell therapy
- Platelet-Rich Plasma (PRP) injections
- Interventional pain management
- Non-surgical spine care
- Electrodiagnostic studies
Conditions Treated: Spine and disc conditions, chronic joint pain, musculoskeletal pain, nerve pain, orthopedic injuries, degenerative conditions
Hours: Monday through Friday, 8:00 AM to 5:00 PM
4. Denver Sports Ortho
Denver Sports Ortho is the practice of Dr. Braden Mayer, a board-certified orthopedic surgeon specializing in shoulder and knee conditions, regenerative medicine, and sports medicine. Dr. Mayer completed a fellowship at the Steadman Hawkins Clinic Denver and an additional traveling fellowship in Complex Shoulder Disorders and Arthroplasty with world-renowned surgeon Professor Christian Gerber in Zurich, Switzerland. He currently serves as Team Physician for the Denver Broncos and Associate Team Physician for the Colorado Rockies. The practice is affiliated with UCHealth Steadman Hawkins Clinic Denver and offers bone marrow concentrate and PRP treatments as non-surgical orthobiologic options for patients with joint and soft tissue conditions.
Address: 175 Inverness Drive West, Suite 200, Englewood, CO 80112
Phone: (303) 694-3333
Website: https://www.denversportsortho.com
Key Personnel:
- Dr. Braden Mayer, MD, Founder, board-certified orthopedic surgeon, fellowship-trained at the Steadman Hawkins Clinic Denver, Team Physician for the Denver Broncos
Services Offered:
- Bone marrow aspirate concentrate (BMAC) procedures
- Platelet-Rich Plasma (PRP) injections
- Orthobiologic treatments for shoulder and knee
- Arthroscopic and reconstructive knee surgery (when indicated)
- Shoulder surgery and cartilage restoration (when indicated)
Conditions Treated: Knee injuries and osteoarthritis, shoulder conditions including rotator cuff and labral tears, ACL injuries, cartilage damage, sports injuries, tendon and ligament conditions
Hours: Monday through Friday, 8:00 AM to 5:00 PM
5. Boulder Biologics
Boulder Biologics is a Boulder-based regenerative medicine practice founded in 2018 and led by Dr. Jason Glowney and Dr. Lauren Rudolph. Dr. Glowney is board-certified in Internal Medicine, Emergency Medicine, and Sports Medicine, completed his sports medicine fellowship at the University of Colorado, and previously served at the CU Sports Medicine and Performance Center. Dr. Rudolph is double board-certified in Sports Medicine and Physical Medicine and Rehabilitation, has extensive experience in diagnostic and interventional musculoskeletal ultrasound and orthobiologics, and serves as Team Physician for U.S. Ski and Snowboard. The practice is employee-owned and operated, emphasizes evidence-informed and FDA-guidance-aligned approaches, and delivers autologous biologic treatments using image-guided techniques.
Address: 4745 Arapahoe Avenue, Suite 300, Boulder, CO 80303
Phone: (720) 550-6175
Website: https://www.boulderbiologics.com
Key Personnel:
- Dr. Jason Glowney, MD, President and Lead Physician, board-certified in Internal Medicine, Emergency Medicine, and Sports Medicine; Sports Medicine fellowship at the University of Colorado
- Dr. Lauren Rudolph, MD, Physician Partner, double board-certified in Sports Medicine and Physical Medicine and Rehabilitation, Team Physician for U.S. Ski and Snowboard
Services Offered:
- Mesenchymal stem cell therapy (autologous)
- Platelet-Rich Plasma (PRP) injections
- Prolotherapy
- Nerve hydrodissection
- Extracorporeal Pulse Activation Technology (EPAT)
Conditions Treated: Knee and hip osteoarthritis, shoulder and rotator cuff conditions, spine and disc conditions, tendon and ligament injuries, nerve pain, sports injuries, degenerative musculoskeletal conditions
6. Denver Regenerative Medicine
Denver Regenerative Medicine is a multi-location Colorado practice established in 2010 and serving the Denver community for over 15 years. The practice is led by Dr. Joel Cherdack, DC, Founder, and Dr. Andrew Hong, MD, and offers the proprietary acCELLerate™ protocol, which combines the patient’s own plasma, platelets, and stem cells into a single regenerative treatment to improve treatment efficacy. The clinic uses image-guided ultrasound for precise delivery of PRP to sites of tendon degeneration or cartilage thinning and serves patients across its Denver location as well as offices in Colorado Springs, Fort Collins, and Grand Junction.
Address: 455 Sherman Street, Suite 450, Denver, CO 80203
Phone: (720) 583-1648
Website: https://denverregenerativemedicine.com
Key Personnel:
- Dr. Joel Cherdack, DC, Founder, Doctor of Chiropractic and regenerative medicine specialist
- Dr. Andrew Hong, MD, Physician and regenerative medicine specialist
Services Offered:
- acCELLerate™ combination stem cell and PRP therapy
- Platelet-Rich Plasma (PRP) injections
- Stem cell therapy
- Hormone replacement therapy
- Non-surgical joint and spine treatments
Conditions Treated: Back pain, knee pain, hip pain, shoulder conditions, joint pain, tendon degeneration, cartilage conditions, hormonal and wellness concerns
About This Directory
This listing is part of a national regenerative medicine directory covering major metropolitan areas across the United States. Clinics included in this directory are real, operating practices with verified addresses and publicly available contact information. Inclusion does not imply endorsement, certification, or quality rating. Patients should independently verify provider credentials, treatment protocols, and regulatory compliance before pursuing any regenerative medicine treatment.
Many regenerative medicine treatments, including stem cell therapy and PRP, are considered investigational by the FDA for most orthopedic and musculoskeletal applications. Insurance coverage for these treatments is generally not available. Patients are encouraged to discuss all treatment options, risks, benefits, and costs with their healthcare provider before making any decisions.
Last updated: March 2026