Nashville and the surrounding communities of Franklin, Brentwood, and Lebanon form one of the Southeast’s most concentrated corridors for regenerative medicine. Anchored by Vanderbilt University Medical Center and a growing number of independent specialty practices, the Nashville metro area gives patients access to both hospital-based cellular therapy programs and outpatient regenerative clinics. Whether you are managing chronic joint pain, recovering from a sports injury, or exploring non-surgical alternatives for degenerative conditions, the providers listed below represent established practices with verified addresses, documented treatment protocols, and publicly available contact information.
This directory is for informational purposes only. It does not constitute medical advice, endorsement, or recommendation. Inclusion in this directory does not imply certification or quality rating. Always consult a qualified healthcare provider before pursuing any treatment.
Quick Guide by Condition
If you are looking for a provider based on your specific concern, this overview may help narrow your search:
Orthopedic and joint conditions (knee, hip, shoulder, spine): All six clinics listed below offer treatments for musculoskeletal pain. Vita Nova, Kellum Stem Cell Institute, and iOBX focus specifically on orthopedic applications and use autologous (patient-derived) cells. R3 Stem Cell and Stem Cell Therapy Center of Nashville use allogeneic (donor-derived) umbilical cord tissue.
Neurological conditions (neuropathy, Parkinson’s, TBI): Stem Cell Therapy Center of Nashville lists neurological conditions among its treatment areas. Interventional Pain Center addresses neuropathic pain through interventional pain management protocols.
Chronic pain management: Interventional Pain Center combines regenerative therapies with a broader pain management program including interventional procedures, prolotherapy, and medical devices.
Anti-aging and wellness: R3 Stem Cell and Stem Cell Therapy Center of Nashville both offer exosome therapy and wellness-oriented regenerative treatments.
1. Vita Nova Stem Cell Professionals
Vita Nova Stem Cell Professionals is a regenerative medicine practice in Franklin, Tennessee, serving patients throughout the greater Nashville area and Middle Tennessee. Founded by Dr. Hemal V. Mehta, a board-certified physician in Physical Medicine and Rehabilitation, the clinic was built on a core principle: the body already contains the ingredients it needs to heal itself. What distinguishes Vita Nova from most regenerative clinics in the region is its in-house laboratory, where autologous cells harvested from the patient’s own body are processed on-site under direct physician supervision rather than being shipped to an external facility. This means the entire process, from cell harvesting to injection, happens in one location during a single visit, giving the clinical team full control over quality at every step.
Every patient who undergoes a stem cell procedure at Vita Nova receives documented cell count and viability reports detailing exactly what is administered. Injections are placed using real-time ultrasound guidance and fluoroscopy imaging, allowing the physician to target the affected tissue with precision. The clinic opened its current facility at 4601 Carothers Parkway in Franklin with a grand opening and ribbon cutting ceremony in February 2026, attended by the Williamson County business community and local civic leaders.
Dr. Mehta is a member of the American Academy of Physical Medicine and Rehabilitation and the American Society of Interventional Pain Physicians, with a clinical philosophy that prioritizes reducing dependency on opioids, avoiding unnecessary surgical procedures, and creating treatment plans tailored to each patient’s condition and goals. Clinical Lead Kate Sherman, PA-C, works directly with patients throughout the evaluation, treatment, and follow-up process.
Address: 4601 Carothers Parkway, Suite 325, Franklin, TN 37067
Phone: (615) 801-8005
Website: vitanovatn.com
Key Personnel:
- Dr. Hemal V. Mehta, MD, Founder and Medical Director, board-certified in Physical Medicine and Rehabilitation, member of the American Academy of Physical Medicine and Rehabilitation and the American Society of Interventional Pain Physicians
- Kate Sherman, PA-C, Clinical Lead
- Brian Clontz, CEO
Services Offered:
- Autologous stem cell therapy (cells harvested and processed from the patient’s own body in the in-house lab, with documented cell count and viability reporting)
- Platelet-Rich Plasma (PRP) therapy for skin rejuvenation and tissue recovery
- Alpha-2-Macroglobulin (A2M) protein therapy for cartilage protection and joint inflammation reduction
- IV nutrient infusion therapy delivering vitamins, minerals, and hydration
Conditions Treated: Orthopedic injuries, chronic joint pain, shoulder pain, knee osteoarthritis, degenerative disc conditions, soft tissue injuries, inflammatory conditions, neurological conditions, autoimmune conditions, wellness and anti-aging
Hours: Monday through Friday, 8:00 AM to 5:00 PM
Email: info@vitanovatn.com
2. iOBX (iOrthoBiologix)
iOBX is an orthopedic stem cell practice headquartered in Charlotte, North Carolina, with a Nashville-area location in Lebanon, Tennessee. The clinic uses autologous stem cells harvested from the patient’s own bone marrow and adipose tissue, processed on-site in its BIOLOGIX laboratory by a PhD lab scientist. iOBX reports harvesting 200 to 300 percent more stem cells than average through its proprietary manual processing technique, with a stated viability rate above 98 percent. All implantations are performed under image-guided precision using fluoroscopy and ultrasound. The practice treats only orthopedic conditions.
Address: 920 South Hartmann Drive, Suite 320, Lebanon, TN 37090
Phone: (980) 859-2340 (Charlotte headquarters line serving all locations)
Website: iobx.com
Key Personnel:
- Board-certified, advanced fellowship-trained orthopedic and sports medicine physicians
- Michael Duncan, PhD, Lab Scientist, BIOLOGIX Laboratory
Services Offered:
- Autologous bone marrow stem cell therapy
- Adipose-derived stem cell therapy
- On-site BIOLOGIX lab processing with cell count and viability verification
- Image-guided precision implantation (fluoroscopy, ultrasound, micro-camera)
Conditions Treated: Knee pain and arthritis, hip osteoarthritis, shoulder injuries, rotator cuff tears, spine conditions, elbow injuries, ankle and foot conditions
Hours: Monday through Friday, 8:30 AM to 5:00 PM
Insurance: Not covered. The practice notes that out-of-pocket costs are often comparable to surgery after deductibles and copays.
3. R3 Stem Cell Nashville
R3 Stem Cell operates a Nashville-area location in Brentwood, Tennessee, as part of a national network with over 45 centers across seven countries. The Brentwood clinic offers stem cell therapy using umbilical cord allograft tissue, exosome therapy, and PRP treatments. R3 reports having performed over 21,000 procedures across its network. The practice provides free initial consultations by phone or in person.
Address: 5020 Thoroughbred Lane, Brentwood, TN 37027 (Merchant’s Walk Shopping Center)
Phone: (844) 438-7836 (844-GET-STEM)
Website: r3stemcell.com/nashville-tn
Key Personnel:
- Dr. David Greene, DO, CEO of R3 Stem Cell
- Local provider staff available at the Brentwood location
Services Offered:
- Umbilical cord tissue stem cell therapy
- Exosome therapy
- Platelet-Rich Plasma (PRP) injections
- Hormone replacement therapy (bioidentical hormones)
- Sexual health treatments
Conditions Treated (as reported by the provider): Knee pain, hip pain, shoulder pain, back pain, neuropathy, erectile dysfunction, autoimmune conditions, COPD, neurological conditions
Pricing: Starts at $2,495 for one extremity joint with umbilical cord stem cells (as reported by the provider)
Insurance: Not covered
4. Interventional Pain Center
Interventional Pain Center is a pain management practice with a Nashville location and a Hendersonville office that offers regenerative therapy alongside its core interventional pain services. The clinic uses umbilical cord Wharton’s Jelly-derived regenerative cells for orthopedic pain conditions. Founded by Dr. Brad Wilson, the practice integrates regenerative protocols into broader chronic pain management plans that may also include prolotherapy, PRP, interventional injections, and durable medical equipment.
Address: 3443 Dickerson Pike, Suite 730, Nashville, TN 37207
Phone: (615) 972-1100
Website: ipcpaincenter.com
Key Personnel:
- Dr. Brad Wilson, DO, Founder, board-certified interventional pain specialist
Services Offered:
- Wharton’s Jelly-derived regenerative cell therapy
- Platelet-Rich Plasma (PRP) therapy
- Prolotherapy
- Interventional pain management procedures
- Durable medical equipment (back, knee, and wrist braces)
Conditions Treated: Knee pain, back pain, hip pain, shoulder pain, chronic pain conditions, degenerative joint disease, tendon and ligament injuries
Hours: Monday through Thursday, 7:00 AM to 5:00 PM; Friday, 8:00 AM to 12:00 PM
Insurance: Regenerative therapies are not covered. Standard pain management services may be covered depending on plan.
Note: The practice states that regenerative therapies including prolotherapy, PRP, and stem cell therapies are considered experimental and are not FDA-approved for these indications.
5. Stem Cell Therapy Center of Nashville
The Stem Cell Therapy Center of Nashville is located in Franklin and offers regenerative treatments using umbilical cord-derived stem cells, exosomes, and PRP. The clinic lists a broad range of treatment areas spanning orthopedic injuries, neurological conditions, autoimmune conditions, and cosmetic applications. The practice emphasizes non-surgical, minimally invasive procedures and reports that most patients begin noticing improvement within 30 days. Condition claims listed below are as reported by the provider and should be discussed with a qualified physician.
Address: 1909 Mallory Lane, Suite 302D, Franklin, TN 37067
Phone: (615) 905-4994
Website: stemcelltherapycenternashville.com
Key Personnel:
- Clinical staff specializing in regenerative medicine (provider names available upon consultation)
Services Offered:
- Umbilical cord-derived stem cell therapy
- Exosome therapy (including anti-aging applications)
- Platelet-Rich Plasma (PRP) injections
- Regenerative cosmetic procedures
Conditions Treated (as reported by the provider): Arthritis, orthopedic injuries, neuropathy, neurological disorders (including Parkinson’s and Alzheimer’s), cardiovascular conditions, COPD, long COVID, diabetes, hair loss, erectile dysfunction, peripheral arterial disease
Insurance: Not covered
About This Directory
This listing is part of a national regenerative medicine directory covering major metropolitan areas across the United States. Clinics included in this directory are real, operating practices with verified addresses and publicly available contact information. Inclusion does not imply endorsement, certification, or quality rating. Patients should independently verify provider credentials, treatment protocols, and regulatory compliance before pursuing any regenerative medicine treatment.
Many regenerative medicine treatments, including stem cell therapy and PRP, are considered investigational by the FDA for most orthopedic and musculoskeletal applications. Insurance coverage for these treatments is generally not available. Patients are encouraged to discuss all treatment options, risks, benefits, and costs with their healthcare provider before making any decisions.
Last updated: March 2026