Chicago and the greater Chicagoland area offer patients access to one of the most diverse concentrations of regenerative medicine providers in the Midwest. The region spans a range of practice types, from university-affiliated orthopedic programs at Rush University Medical Center to independent specialty clinics in city neighborhoods and western suburbs. Providers across Cook, DuPage, and Will counties offer autologous and allogeneic cell therapies, platelet-rich plasma protocols, prolotherapy, exosome treatments, and advanced biologic injections for orthopedic and pain conditions. The providers listed below represent established practices with verified addresses, documented treatment offerings, and publicly available contact information.
This directory is for informational purposes only. It does not constitute medical advice, endorsement, or recommendation. Inclusion in this directory does not imply certification or quality rating. Always consult a qualified healthcare provider before pursuing any treatment.
Quick Guide by Condition
If you are looking for a provider based on your specific concern, this overview may help narrow your search:
Orthopedic and joint conditions (knee, hip, shoulder, spine): Chicago Arthritis and Regenerative Medicine, Midwest Orthopaedics at Rush (Dr. Chahla), and the Prodromos Stem Cell Institute all specialize in orthopedic biologic therapies. Dr. Chahla serves as a team physician for Chicago professional sports organizations.
Chronic pain management: Chicago Stem Cell Therapy and Pain Management Institute and Gateway Regenerative Institute combine regenerative cell therapies with comprehensive pain management protocols for spine and joint conditions.
Broad systemic and neurological conditions (as reported by providers): The Prodromos Stem Cell Institute and NovoCellMD offer regenerative protocols for conditions beyond orthopedics, including autoimmune and neurological applications.
1. Chicago Arthritis and Regenerative Medicine
Chicago Arthritis and Regenerative Medicine is a rheumatology and regenerative orthopedics practice led by Dr. Siddharth Tambar, who received his medical degree from the State University of New York at Syracuse and completed both his internal medicine and rheumatology training at Northwestern Memorial Hospital in Chicago. The practice is a certified Regenexx provider and offers platelet-rich plasma and bone marrow concentrate procedures for musculoskeletal conditions. Dr. Tambar focuses on non-surgical treatments for arthritis, tendinitis, injuries, and back pain, integrating regenerative medicine into a comprehensive rheumatology and musculoskeletal health program. In-person visits are available at the Chicago and Glenview locations.
Address: 618 West Fulton Street, Chicago, IL 60661
Phone: (773) 348-7171
Website: https://chicagoarthritis.com
Key Personnel:
- Dr. Siddharth Tambar, MD, Founder, rheumatologist, trained at Northwestern Memorial Hospital
Services Offered:
- Platelet-Rich Plasma (PRP) therapy
- Bone marrow concentrate procedures (Regenexx protocol)
- Non-surgical orthopedic and rheumatologic management
- Regenerative medicine consultation
Conditions Treated: Knee osteoarthritis, hip pain, shoulder tendinitis, back pain, rheumatoid arthritis, ankylosing spondylitis, sports injuries, degenerative joint conditions
2. Midwest Orthopaedics at Rush
Midwest Orthopaedics at Rush is the private practice affiliated with Rush University Medical Center, one of the leading orthopedic programs in the United States. Dr. Jorge Chahla, MD, PhD, is an Associate Professor of Orthopedic Surgery at Rush University and Director of Biomechanical Research and of the International Fellowship Program. Dr. Chahla serves as team physician for the Chicago White Sox, the Chicago Bulls, and the Chicago Fire, and is an internationally recognized pioneer in biological treatments for knee and hip sports injuries. He has published extensively on biologic injections including platelet-rich plasma and bone marrow aspirate concentrate and is a member of the Biologics Alliance.
Address: 1611 West Harrison Street, Chicago, IL 60612
Phone: (312) 432-2531
Website: https://www.jorgechahlamd.com
Key Personnel:
- Dr. Jorge Chahla, MD, PhD, Associate Professor of Orthopedic Surgery at Rush University, team physician for the Chicago White Sox, Chicago Bulls, and Chicago Fire
Services Offered:
- Bone Marrow Aspirate Concentrate (BMAC) therapy
- Platelet-Rich Plasma (PRP) injections
- Stem cell biologic injections
- Hyaluronic acid gel injections
- Advanced orthopedic surgery
Conditions Treated: Knee injuries and arthritis, hip conditions including labral tears, shoulder injuries, rotator cuff conditions, sports-related ligament and tendon injuries, cartilage damage
3. Prodromos Stem Cell Institute
The Prodromos Stem Cell Institute is a Glenview-based regenerative medicine practice led by Dr. Chadwick Prodromos, a board-certified orthopedic surgeon who received his MD from Johns Hopkins Medical School, completed an orthopedic surgery residency at Rush University, and a fellowship in orthopedic surgery and sports medicine at Harvard Medical School and Massachusetts General Hospital. He was an assistant professor of orthopedic surgery at Rush University for 27 years. The institute prioritizes evidence-based care and has an active research and publication record. Dr. Prodromos conducts no-cost remote evaluations for patients across the country.
Address: 1714 North Milwaukee Avenue, Glenview, IL 60025
Phone: (847) 699-6810
Website: https://www.thepsci.com
Key Personnel:
- Dr. Chadwick C. Prodromos, MD, Founder, board-certified orthopedic surgeon, Johns Hopkins MD, Harvard fellowship, former Rush University faculty
Services Offered:
- Mesenchymal stem cell therapy
- Platelet-Rich Plasma (PRP) therapy
- Exosome therapy
- Regenerative orthopedic treatments
Conditions Treated (as reported by the provider): Arthritis, back and neck pain, knee and hip conditions, sports injuries, autoimmune disorders, Parkinson’s disease, ALS, anti-aging and longevity
4. Chicago Stem Cell Therapy and Pain Management Institute
Chicago Stem Cell Therapy and Pain Management Institute is a Joint Commission-accredited clinic in Frankfort, Illinois led by Dr. Zaki Anwar, a board-certified anesthesiologist and interventional pain management physician. Dr. Anwar is a nationally recognized specialist in non-surgical pain management who has dedicated his practice to developing advanced alternatives to surgical intervention. The clinic uses exosome-based regenerative treatments and PRP therapies founded on evidence-based pain management principles.
Address: 10181 West Lincoln Highway, Frankfort, IL 60423
Phone: (815) 464-7212
Website: https://www.chicagostemcelltherapy.com
Key Personnel:
- Dr. Zaki Anwar, MD, Founder and Medical Director, board-certified anesthesiologist and interventional pain management physician
Services Offered:
- Exosome-based regenerative treatments
- Platelet-Rich Plasma (PRP) injections
- Interventional pain management
- Non-surgical spine and joint therapies
Conditions Treated: Degenerative disc disease, spinal arthritis, knee osteoarthritis, hip pain, shoulder pain, chronic musculoskeletal pain, sports injuries
5. NovoCellMD
NovoCellMD is a physician-led stem cell and regenerative medicine clinic in Chicago’s Lincoln Park neighborhood offering mesenchymal stem cell treatments derived from ethically sourced umbilical cord tissue. The clinic is led by Dr. Anand Thakkar, a board-certified physician, and conducts all consultations and treatments under direct physician supervision. NovoCellMD also serves the Schaumburg area and maintains affiliations with R3 Stem Cell and international regenerative medicine partners. The practice focuses on orthopedic, autoimmune, and wellness applications.
Address: 2707 North Halsted Street, Suite 101, Chicago, IL 60614
Phone: (224) 353-0279
Website: https://novocellmd.com
Key Personnel:
- Dr. Anand Thakkar, MD, Founder, board-certified physician with advanced training in regenerative medicine
Services Offered:
- Mesenchymal stem cell therapy (umbilical cord-derived)
- Platelet-Rich Plasma (PRP) therapy
- Exosome therapy
- Non-surgical joint and pain treatments
Conditions Treated (as reported by the provider): Joint pain, arthritis, sports injuries, autoimmune disease, neurological recovery, sexual wellness
6. Gateway Regenerative Institute
Gateway Regenerative Institute is a Hinsdale-based regenerative medicine practice affiliated with Gateway Spine and Pain Physicians, the largest independent comprehensive pain practice in the Chicago region. The institute is led by Dr. John K. Hong, who is double board-certified in Pain Medicine and Anesthesiology by the American Board of Anesthesiology. Dr. Hong received his medical degrees at Cornell and Tufts Universities, completed an anesthesiology residency at Rush University Medical Center, and a pain medicine fellowship at the University of Illinois at Chicago. The institute offers both established regenerative treatments and advanced next-generation biologics including exosomes and alpha-2-macroglobulin.
Address: 12 Salt Creek Lane, Suite 106, Hinsdale, IL 60521
Phone: (630) 226-1130
Website: https://www.gatewayregen.com
Key Personnel:
- Dr. John K. Hong, MD, Founder and Medical Director, double board-certified in Pain Medicine and Anesthesiology, Rush University residency, University of Illinois pain fellowship
Services Offered:
- Stem cell and PRP injections
- Exosome therapy
- Alpha-2-macroglobulin (A2M) injections
- Platelet-Rich Fibrin Matrix (PRFM) therapy
- Comprehensive pain management
Conditions Treated: Knee pain and arthritis, hip pain, shoulder conditions, spine-related conditions, tendon and ligament injuries, chronic musculoskeletal pain
About This Directory
This listing is part of a national regenerative medicine directory covering major metropolitan areas across the United States. Clinics included in this directory are real, operating practices with verified addresses and publicly available contact information. Inclusion does not imply endorsement, certification, or quality rating. Patients should independently verify provider credentials, treatment protocols, and regulatory compliance before pursuing any regenerative medicine treatment.
Many regenerative medicine treatments, including stem cell therapy and PRP, are considered investigational by the FDA for most orthopedic and musculoskeletal applications. Insurance coverage for these treatments is generally not available. Patients are encouraged to discuss all treatment options, risks, benefits, and costs with their healthcare provider before making any decisions.
Last updated: March 2026