The Dallas-Fort Worth metroplex is one of the fastest-growing medical markets in the United States and supports a substantial concentration of regenerative medicine practices across Dallas, Plano, Frisco, Southlake, and surrounding communities. The region draws patients from across North Texas and neighboring states, with providers ranging from nationally recognized adipose-derived stem cell specialists to orthopedic surgeons and osteopathic physicians offering evidence-based biologic therapies. The providers listed below represent established practices with verified addresses, documented treatment offerings, and publicly available contact information.
This directory is for informational purposes only. It does not constitute medical advice, endorsement, or recommendation. Inclusion in this directory does not imply certification or quality rating. Always consult a qualified healthcare provider before pursuing any treatment.
Quick Guide by Condition
If you are looking for a provider based on your specific concern, this overview may help narrow your search:
Orthopedic and joint conditions (knee, hip, shoulder, spine): Texas Orthobiologics, RegenOrthoSport, North Texas Musculoskeletal Medicine, and Dallas Hip and Knee all specialize in orthopedic biologic applications using autologous methods. RegenOrthoSport is Texas’s first Regenexx network provider.
Adipose-derived and autologous cell therapies: Innovations Stem Cell Center is a nationally recognized leader in adipose-derived stem cell therapy with an on-site FDA-compliant laboratory and over 12 years of procedure experience.
Chronic pain and interventional management: The Integrative Pain Institute combines evidence-based pain management with regenerative cell therapies for chronic musculoskeletal conditions.
1. Innovations Stem Cell Center
Innovations Stem Cell Center is a Dallas practice founded by Dr. Bill Johnson, a physician who has specialized in adipose-derived stem cell therapy since 2013 and has performed thousands of procedures. The center operates an on-site FDA-compliant laboratory where stem cells are harvested and processed from the patient’s own fat tissue, with no outsourcing of cell processing. Life Sciences Review Magazine has recognized the center as the nation’s top stem cell clinic. Dr. Johnson is a regular contributor to Dallas media including appearances on ABC, FOX, NBC, and CBS, and on Good Morning Texas. The facility is centrally located approximately 15 minutes from Love Field Airport.
Address: 12660 Coit Road, Suite 100, Dallas, TX 75251
Phone: (214) 420-7970
Website: https://innovationsstemcellcenter.com
Key Personnel:
- Dr. Bill Johnson, MD, Founder, internal medicine physician, pioneer in adipose-derived stem cell therapy with over 12 years of procedure experience
Services Offered:
- Adipose-derived autologous stem cell therapy (in-house processing)
- Platelet-Rich Plasma (PRP) therapy
- Anti-aging and longevity stem cell protocols
- Orthopedic biologic treatments
Conditions Treated (as reported by the provider): Orthopedic injuries, joint pain, arthritis, degenerative conditions, autoimmune disorders, anti-aging and longevity wellness
2. Texas Orthobiologics
Texas Orthobiologics is a Dallas orthopedic and regenerative medicine practice founded by Dr. Don Buford, a board-certified orthopedic surgeon who has been practicing in Dallas for over 20 years and has been voted among the best orthopedic surgeons in the Dallas area by his peers. Dr. Buford served as the 2021 President of the Interventional Orthobiologics Foundation and serves on the Board of the Arthroscopy Association of North America from 2023 to 2026. The practice uses only patient-derived biological material to minimize risk, and functions as a clinical research institute working to advance knowledge in regenerative medicine. All biologic treatments are derived from the patient’s own bone marrow.
Address: 3310 Live Oak Street, Suite 202, Dallas, TX 75204
Phone: (877) 777-8883
Website: https://www.texasorthobiologics.com
Key Personnel:
- Dr. Don Buford, MD, Founder, board-certified orthopedic surgeon, 2021 President of the Interventional Orthobiologics Foundation
Services Offered:
- Bone marrow concentrate (BMAC) therapy
- Platelet-Rich Plasma (PRP) injections
- Orthopedic surgery (when indicated)
- Clinical research in regenerative orthopedics
Conditions Treated: Arthritis, back pain, tendon injuries, sports injuries, knee osteoarthritis, hip pain, shoulder conditions, degenerative joint disease
3. RegenOrthoSport
RegenOrthoSport is a Dallas practice led by Dr. Venkatesh Movva, a fellowship-trained sports medicine physician and board-certified pain management specialist who is recognized as Texas’s first Regenexx network provider. Dr. Movva founded RegenOrthoSport to advance non-invasive orthopedic treatments and has treated thousands of patients with knee, shoulder, spine, and hip conditions. The practice uses ultrasound and fluoroscopy guidance for precise injection delivery. Dr. Movva is a pioneer in regenerative orthopedics in the North Texas region.
Address: 7859 Walnut Hill Lane, Suite 340, Dallas, TX 75230
Phone: (817) 442-9292
Website: https://regenorthosport.com
Key Personnel:
- Dr. Venkatesh Movva, MD, Founder, fellowship-trained in Sports Medicine, board-certified in Pain Management, Texas’s first Regenexx network provider
Services Offered:
- Stem cell therapy (Regenexx protocol)
- Platelet-Rich Plasma (PRP) injections
- Bone marrow concentrate procedures
- Ultrasound and fluoroscopy-guided injections
- Non-surgical spine and joint treatments
Conditions Treated: Knee osteoarthritis, shoulder conditions, hip pain, spine-related conditions, sports injuries, tendon and ligament damage, degenerative joint disease
Hours: Monday through Friday, 9:00 AM to 4:30 PM
4. North Texas Musculoskeletal Medicine
North Texas Musculoskeletal Medicine is a Southlake practice led by Dr. Dennis E. Minotti II, a doctor of osteopathic medicine who is board-certified by the American Board of Neuromusculoskeletal Medicine and specialty-trained in Regenerative Orthopedics. Dr. Minotti also serves as an adjunct professor at the University of North Texas Health Science Center and has been voted among the best regenerative medicine specialists in the Dallas-Fort Worth area by his peers. The practice combines regenerative biologic treatments with osteopathic manipulative medicine and offers a broad range of non-surgical orthopedic therapies.
Address: 230 Miron Drive, Suite 110, Southlake, TX 76092
Phone: (817) 416-0970
Website: https://www.ntxmsk.com
Key Personnel:
- Dr. Dennis E. Minotti II, DO, Founder, board-certified by the American Board of Neuromusculoskeletal Medicine, adjunct professor at UNT Health Science Center
Services Offered:
- Stem cell therapy
- Platelet-Rich Plasma (PRP) injections
- Osteopathic manipulative medicine
- Prolotherapy
- Viscosupplementation
- Extracorporeal shock wave therapy
Conditions Treated: Knee pain and osteoarthritis, hip conditions, shoulder injuries, spine conditions, tendon and ligament injuries, sports injuries, degenerative musculoskeletal conditions
Hours: Monday through Friday, 9:00 AM to 5:00 PM
5. Integrative Pain Institute
The Integrative Pain Institute is a Dallas pain management practice offering regenerative cell therapy alongside a comprehensive pain management program. The practice serves patients in Dallas, Plano, and McKinney and uses bone marrow-derived stem cells as part of a multi-modal approach to chronic and acute pain. The team of specialists includes pain management physicians, sports medicine doctors, and arthritis specialists who focus on addressing the underlying causes of pain rather than masking symptoms.
Address: 15110 North Dallas Parkway, Suite 102, Dallas, TX 75248
Phone: (972) 290-1506
Website: https://www.integrativepaininstitute.com
Key Personnel:
- Provider names available upon consultation
Services Offered:
- Bone marrow-derived stem cell therapy
- Platelet-Rich Plasma (PRP) therapy
- Interventional pain management
- Sports medicine consultation
- Comprehensive chronic pain programs
Conditions Treated: Knee pain, back pain, sciatica, fibromyalgia, diabetic neuropathy, sports injuries, arthritis, degenerative joint conditions
6. Dallas Hip and Knee Orthopaedics
Dallas Hip and Knee Orthopaedics is a multi-location orthopedic practice led by Dr. Khalid Yousuf, a board-certified orthopedic surgeon who completed a fellowship in adult reconstructive orthopaedics at the Mayo Clinic College of Medicine and Science. Dr. Yousuf serves as Adjunct Assistant Professor at Texas A&M University College of Medicine and has been named among the best doctors in Dallas and Collin County. The practice offers stem cell therapy and regenerative medicine as non-surgical alternatives for patients managing joint pain and degenerative conditions at multiple North Texas locations.
Address: 4716 Alliance Boulevard, Pavilion II, Suite 600, Plano, TX 75093
Phone: (469) 800-7200
Website: https://www.dallashipknee.com
Key Personnel:
- Dr. Khalid Yousuf, MD, Founder, board-certified orthopedic surgeon, Mayo Clinic fellowship in adult reconstructive orthopaedics, Adjunct Assistant Professor at Texas A&M University College of Medicine
Services Offered:
- Stem cell therapy
- Platelet-Rich Plasma (PRP) injections
- Orthopedic joint preservation
- Robotic joint replacement surgery (when indicated)
Conditions Treated: Knee osteoarthritis, hip pain, shoulder conditions, joint degeneration, sports injuries, degenerative joint disease
About This Directory
This listing is part of a national regenerative medicine directory covering major metropolitan areas across the United States. Clinics included in this directory are real, operating practices with verified addresses and publicly available contact information. Inclusion does not imply endorsement, certification, or quality rating. Patients should independently verify provider credentials, treatment protocols, and regulatory compliance before pursuing any regenerative medicine treatment.
Many regenerative medicine treatments, including stem cell therapy and PRP, are considered investigational by the FDA for most orthopedic and musculoskeletal applications. Insurance coverage for these treatments is generally not available. Patients are encouraged to discuss all treatment options, risks, benefits, and costs with their healthcare provider before making any decisions.
Last updated: March 2026