The Phoenix and Scottsdale metropolitan area is one of the most active markets for regenerative medicine in the American Southwest. R3 Stem Cell, a national network with its corporate headquarters in Scottsdale, calls the region home, and the broader Phoenix metro supports a significant concentration of independent specialty practices offering autologous and allogeneic cell therapies, prolotherapy, platelet-rich plasma treatments, and integrative regenerative protocols. Patients in communities across Maricopa County, including Mesa, Chandler, Gilbert, and Tempe, have access to providers ranging from board-certified orthopedic surgeons to naturopathic and integrative medicine physicians. The providers listed below represent established practices with verified addresses, documented treatment offerings, and publicly available contact information.
This directory is for informational purposes only. It does not constitute medical advice, endorsement, or recommendation. Inclusion in this directory does not imply certification or quality rating. Always consult a qualified healthcare provider before pursuing any treatment.
Quick Guide by Condition
If you are looking for a provider based on your specific concern, this overview may help narrow your search:
Orthopedic and joint conditions (knee, hip, shoulder, spine): Precision Regenerative Medicine, Dr. Anup Shah, and R3 Stem Cell Scottsdale all offer orthopedic biologic therapies. Arizona Prolotherapy focuses exclusively on regenerative injection therapies including prolotherapy and PRP for musculoskeletal conditions.
Integrative and naturopathic approaches: Innate Healthcare Institute and Stem Cell for Life provide integrative and naturopathic regenerative protocols that combine cellular therapies with holistic health strategies including hormone optimization, frequency medicine, and nutrition.
Chronic pain and anti-aging: Innate Healthcare Institute and R3 Stem Cell Scottsdale both offer exosome therapy and hormone replacement alongside their orthopedic services.
1. Precision Regenerative Medicine
Precision Regenerative Medicine is a specialty regenerative clinic in Scottsdale led by Dr. Tammy Penhollow, a double board-certified physician in Anesthesiology and Pain Management who trained at Stanford and the U.S. Navy, and serves as an Instructor in Anesthesiology at the Mayo Clinic College of Medicine and Science. The clinic uses orthobiologic cell therapy derived from the patient’s own blood, bone marrow, or adipose tissue for musculoskeletal conditions affecting joints, muscles, tendons, ligaments, and the spine. Dr. Penhollow is a former active-duty U.S. Naval Officer who has practiced and deployed across the United States and internationally, and brings a personalized non-surgical approach to pain management and regenerative care.
Address: 9700 North 91st Street, Suite A-115, Scottsdale, AZ 85258
Phone: (602) 899-7002
Website: https://precisionmedprp.com
Key Personnel:
- Dr. Tammy Penhollow, DO, Founder, double board-certified in Anesthesiology (U.S. Navy) and Pain Management (Stanford), Instructor at Mayo Clinic College of Medicine and Science
Services Offered:
- Orthobiologic cell therapy (blood, bone marrow, and adipose-derived)
- Platelet-Rich Plasma (PRP) injections
- Non-surgical pain management
- Injury rehabilitation
Conditions Treated: Joint pain, tendon and ligament injuries, spine conditions, muscle injuries, arthritis, chronic pain, acute orthopedic injuries
2. Arizona Prolotherapy
Arizona Prolotherapy is a Scottsdale clinic devoted exclusively to regenerative orthopedic injection therapies, led by Dr. David A. Tallman, a licensed chiropractor and naturopathic medical doctor with over two decades of experience in prolotherapy and regenerative orthopedics. Dr. Tallman has performed tens of thousands of prolotherapy and platelet-rich plasma procedures and is recognized as one of the most experienced practitioners of orthopedic regenerative injection therapies in the Southwest. The clinic uses radiology-grade diagnostic ultrasound for tissue visualization and precision-guided injections.
Address: 8300 North Hayden Road, Suite A111, Scottsdale, AZ 85258
Phone: (480) 922-1101
Website: https://arizonaprolotherapy.com
Key Personnel:
- Dr. David A. Tallman, DC, NMD, Founder, licensed chiropractor and naturopathic medical doctor, regenerative orthopedics specialist with over 20 years of clinical experience
Services Offered:
- Prolotherapy injections
- Platelet-Rich Plasma (PRP) therapy
- Bone Marrow Aspirate Concentrate (BMAC) therapy
- Ultrasound-guided regenerative injections
Conditions Treated: Chronic joint pain, tendon injuries, ligament damage, osteoarthritis, spine conditions, rotator cuff conditions, knee pain, hip pain, sports injuries, soft tissue damage
3. Anup Shah, MD
Dr. Anup Shah is a double board-certified orthopedic surgeon specializing in sports medicine and shoulder surgery who practices in Phoenix and Scottsdale, Arizona. Dr. Shah completed an Orthopedic Sports Medicine Fellowship at Baylor College of Medicine and a Shoulder and Elbow Fellowship at Harvard Medical School and Massachusetts General Hospital. He also holds an MBA from Rice University. He is a Fellow of the American Academy of Orthopaedic Surgeons (FAAOS) and holds a Certificate of Added Qualification in Sports Medicine. He has over 30 peer-reviewed publications and is active in national orthopedic society committees. His orthobiologic offerings include bone marrow aspirate concentrate and PRP for patients seeking non-surgical options.
Address: 755 East McDowell Road, Phoenix, AZ 85006
Phone: (602) 521-3250
Website: https://www.orthoshah.com
Key Personnel:
- Dr. Anup Shah, MD, MBA, FAAOS, double board-certified orthopedic surgeon, fellowship-trained at Baylor College of Medicine and Harvard Medical School / Massachusetts General Hospital
Services Offered:
- Bone Marrow Aspirate Concentrate (BMAC) therapy
- Platelet-Rich Plasma (PRP) injections
- Orthobiologic treatments for joint preservation
- Orthopedic surgery (when indicated)
Conditions Treated: Knee injuries and osteoarthritis, shoulder injuries including rotator cuff and labral tears, hip conditions, tendon and ligament damage, sports-related musculoskeletal injuries, degenerative joint conditions
4. Innate Healthcare Institute
Innate Healthcare Institute is a Scottsdale integrative and regenerative medicine clinic that blends modern functional, regenerative, and traditional medicine approaches. The clinic is led by Dr. Travis Whitney, a naturopathic medical doctor, and offers biological regenerative therapies including cellular medicine and exosome treatments alongside bioidentical hormone replacement and integrative health protocols. Innate Healthcare is recognized as a pioneering clinic in the use of stem cell therapy and regenerative medicine in the Phoenix metro region and draws patients from around the country and internationally.
Address: 4835 East Cactus Road, Suite 140, Scottsdale, AZ 85254
Phone: (602) 603-3118
Website: https://innatehealthcare.org
Key Personnel:
- Dr. Travis Whitney, NMD, Lead Physician, naturopathic medical doctor specializing in regenerative and integrative medicine
Services Offered:
- Regenerative cellular medicine and exosome therapy
- Bioidentical hormone replacement therapy
- Functional medicine consultation
- Integrative health protocols
Conditions Treated (as reported by the provider): Joint pain, orthopedic conditions, anti-aging and hormone imbalance, fatigue, chronic conditions, wellness and longevity
Hours: Monday through Thursday, 9:00 AM to 5:00 PM
5. R3 Stem Cell Scottsdale
R3 Stem Cell operates a Scottsdale clinic as part of its national and international network of over 45 centers. R3 is headquartered in the Scottsdale area and reports having performed over 21,000 stem cell and exosome procedures as well as 100,000 platelet-rich plasma injections across its network. The Scottsdale clinic offers umbilical cord allograft stem cell therapy, exosome treatments, and PRP for orthopedic conditions. Free consultations are available by phone or in person.
Address: 978 North 91st Street, Suite 101, Scottsdale, AZ 85258
Phone: (480) 306-6256
Website: https://r3stemcell.com/scottsdale-az/regenerative-medicine
Key Personnel:
- Dr. David Greene, DO, CEO of R3 Stem Cell
- Local provider staff at the Scottsdale location
Services Offered:
- Umbilical cord tissue stem cell therapy
- Exosome therapy
- Platelet-Rich Plasma (PRP) injections
- Hormone replacement therapy
Conditions Treated (as reported by the provider): Knee pain, hip pain, shoulder pain, back pain, neuropathy, erectile dysfunction, autoimmune conditions, COPD, neurological conditions
Insurance: Not covered
6. Stem Cell for Life
Stem Cell for Life is a Phoenix regenerative and naturopathic medicine clinic offering stem cell injections alongside a broader integrative health program that incorporates frequency medicine, anti-inflammatory nutrition, and supplement therapies. The clinic is led by Dr. Jane Hendricks, a naturopathic physician, and focuses on improving and potentially reversing inflammatory and pain conditions through combined regenerative approaches. Stem cell treatments are combined with other supportive therapies to address the underlying causes of tissue damage and chronic disease.
Address: 4050 East Greenway Road, Suite 5, Phoenix, AZ 85032
Phone: (480) 334-8278
Website: https://stemcellforlife.com
Key Personnel:
- Dr. Jane Hendricks, NMD, Lead Physician, naturopathic physician specializing in regenerative and integrative medicine
Services Offered:
- Stem cell injections
- Platelet-Rich Plasma (PRP) therapy
- Frequency medicine
- IV nutrient infusions
- Nutritional and supplement consultation
Conditions Treated (as reported by the provider): Chronic joint pain, inflammatory conditions, degenerative conditions, orthopedic injuries, digestive disorders, wellness and anti-aging
Hours: Monday through Friday, 9:00 AM to 5:00 PM (Saturday 11:00 AM to 2:00 PM)
Insurance: HSA and FSA cards accepted; patient financing available
About This Directory
This listing is part of a national regenerative medicine directory covering major metropolitan areas across the United States. Clinics included in this directory are real, operating practices with verified addresses and publicly available contact information. Inclusion does not imply endorsement, certification, or quality rating. Patients should independently verify provider credentials, treatment protocols, and regulatory compliance before pursuing any regenerative medicine treatment.
Many regenerative medicine treatments, including stem cell therapy and PRP, are considered investigational by the FDA for most orthopedic and musculoskeletal applications. Insurance coverage for these treatments is generally not available. Patients are encouraged to discuss all treatment options, risks, benefits, and costs with their healthcare provider before making any decisions.
Last updated: March 2026