The greater San Jose metropolitan area, including Campbell, Los Gatos, and surrounding Santa Clara County communities, supports a well-developed regenerative medicine market driven by Silicon Valley’s high-performance culture and access to Stanford University and UC Davis medical training programs. San Jose-area providers include a USC Keck-trained orthopedic surgeon who served as Chief of Orthopedics at a major San Jose hospital, a fellowship-trained orthopedic surgeon who serves as team physician for San Jose State University, Santa Clara University, and the San Francisco Giants, a Brown-trained orthopedic surgeon with a UC Davis sports medicine fellowship and UCSF faculty appointment, an orthopedic surgeon who completed a Stanford joint replacement fellowship and has practiced in Los Gatos since 1993, and a dual board-certified orthopedic surgery and sports medicine physician who trained under nationally recognized knee surgeons Christopher Harner and Freddie Fu. The providers listed below represent established practices with verified addresses, documented treatment offerings, and publicly available contact information.
This directory is for informational purposes only. It does not constitute medical advice, endorsement, or recommendation. Inclusion in this directory does not imply certification or quality rating. Always consult a qualified healthcare provider before pursuing any treatment.
Quick Guide by Condition
If you are looking for a provider based on your specific concern, this overview may help narrow your search:
University-based orthopedic surgery with long-established San Jose practices: Dr. Pamela Mehta at Resilience Orthopedics trained at USC Keck School of Medicine and completed her orthopedic surgery residency at Columbia University under Dr. Louis Bigliani, a pioneer in modern shoulder replacement, and served as Chief of Orthopedics at Regional Medical Center in San Jose. Dr. Terence Delaney in Los Gatos completed a joint replacement fellowship at Stanford University and has been in private practice in the greater San Jose area since 1993, and was among the first physicians in the area to offer PRP therapy.
Fellowship-trained orthopedic surgery with professional and collegiate sports medicine credentials: Dr. Kerisimasi Reynolds at MASI Clinic completed a sports medicine and arthroscopy fellowship at the SOAR program and serves as team physician for San Jose State University, Santa Clara University, and the San Francisco Giants. Dr. Jothi Murali-Larson at Smart Orthopaedic Surgery completed her residency at Brown University and an Orthopaedic Sports Medicine fellowship at UC Davis and holds an associate faculty appointment at UCSF.
Board-certified orthopedic surgery and sports medicine with trauma training: Dr. Samir Sharma at South Bay Orthopedic and Sports Medicine graduated at the top of his class with Alpha Omega Alpha honors from Wayne State University School of Medicine, completed a sports medicine externship under Harner and Fu at the University of Pittsburgh, and is dual board-certified in Orthopedic Surgery and Sports Medicine.
1. Resilience Orthopedics
Resilience Orthopedics in San Jose is the practice of Dr. Pamela Mehta, a board-certified orthopedic surgeon who founded the practice and serves patients across the South Bay including San Jose, Los Gatos, Saratoga, Cupertino, Sunnyvale, Santa Clara, Mountain View, and Los Altos. Dr. Mehta earned her undergraduate degree from the University of Southern California, graduating with honors in Biology and Religion, and her medical degree from USC’s Keck School of Medicine. She completed her orthopedic surgery residency at Columbia University, where she trained under Dr. Louis Bigliani, a nationally recognized pioneer in modern shoulder replacement surgery. She is board-certified by the American Board of Orthopaedic Surgery and is a member of the American Academy of Orthopaedic Surgeons. She served as Chief of Orthopedics at Regional Medical Center in San Jose and as National Orthopedic Director for a major orthopedic hospitalist network, and brings more than 20 years of orthopedic experience to her practice. She offers BMAC therapy and platelet-rich plasma alongside a full range of orthopedic surgical services and has maintained a high patient satisfaction record across major physician rating platforms.
Address: 2430 Samaritan Drive, San Jose, CA 95124
Phone: (408) 559-3888
Website: https://www.resilienceorthopedics.com
Key Personnel:
- Dr. Pamela Mehta, MD, Founder, board-certified orthopedic surgeon, USC Keck School of Medicine MD, Columbia University orthopedic surgery residency (trained under Dr. Louis Bigliani), ABOS board-certified, AAOS member, former Chief of Orthopedics Regional Medical Center San Jose, 20+ years of experience
Services Offered:
- Bone Marrow Aspirate Concentrate (BMAC) therapy
- Platelet-Rich Plasma (PRP) therapy
- Stem cell therapy
- Orthopedic surgery and joint replacement (when indicated)
- Sports medicine evaluation and treatment
Conditions Treated: Knee and hip osteoarthritis, shoulder injuries, tendon and ligament injuries, sports injuries, joint conditions in patients seeking alternatives to or planning for joint replacement surgery
2. MASI Clinic
MASI Clinic in San Jose is the practice of Dr. Kerisimasi Reynolds, a board-certified and fellowship-trained orthopedic surgeon specializing in sports medicine, joint preservation, and regenerative orthopedic treatment, who serves as team physician for San Jose State University Athletics, Santa Clara University Athletics, and the San Francisco Giants. Dr. Reynolds earned his undergraduate degree from Oregon State University and his DO degree from Touro University California College of Osteopathic Medicine in 2010. He completed his orthopedic surgery internship and residency through Michigan State University at Henry Ford Health Systems in Detroit. He then completed his fellowship in Sports Medicine and advanced arthroscopy through the Sports Orthopedic and Rehabilitation (SOAR) ACGME-accredited program in the San Francisco Bay Area, where he trained under Dr. Kenneth Akizuki and assisted with the San Francisco Giants organization, gaining experience in advanced cartilage restoration and lower limb realignment procedures. He is a board-certified orthopedic surgeon with subspecialty training in sports medicine and arthroscopy. The MASI Clinic offers PRP, stem cell therapy, and peptide-based anti-inflammatory protocols alongside joint preservation surgery and advanced arthroscopy for athletes and active patients at all levels. The practice relocated from Fremont to San Jose in March 2026.
Address: 550 S Winchester Boulevard, Suite 320, San Jose, CA 95128
Phone: (510) 739-6520
Website: https://masiclinic.com
Key Personnel:
- Dr. Kerisimasi Reynolds, DO, Founder, board-certified orthopedic surgeon fellowship-trained in sports medicine and arthroscopy, Touro University California College of Osteopathic Medicine DO (2010), Michigan State University/Henry Ford Health Systems orthopedic surgery residency, SOAR ACGME-accredited sports medicine fellowship (trained under Dr. Kenneth Akizuki), team physician San Jose State University, Santa Clara University, and San Francisco Giants
Services Offered:
- Platelet-Rich Plasma (PRP) therapy
- Stem cell therapy
- Peptide and anti-inflammatory protocols
- Joint preservation procedures (hyaluronic acid, osteochondral autograft)
- Arthroscopic and reconstructive surgery of the knee, shoulder, hip, and elbow (when indicated)
- Joint replacement (when indicated)
Conditions Treated: Hip and knee osteoarthritis, shoulder pain, knee cartilage conditions, labral tears, sports injuries, tendon and ligament injuries, joint conditions in athletes and active patients seeking minimally invasive or regenerative care
3. Smart Orthopaedic Surgery
Smart Orthopaedic Surgery in San Jose and Campbell is the practice of Dr. Jothi Murali-Larson, a board-certified orthopedic surgeon subspecializing in sports medicine and trauma who has been treating patients in the South Bay since 2016. Dr. Murali-Larson earned her medical degree from Emory University School of Medicine in Atlanta and completed her orthopedic surgery residency at Brown University in Providence, Rhode Island. She then completed a fellowship in Orthopedic Trauma at Rhode Island Hospital and Brown Alpert Medical School and a fellowship in Orthopaedic Sports Medicine at the UC Davis Health System in Sacramento. She is board-certified by the American Board of Orthopaedic Surgery and holds an associate faculty appointment in the Department of Orthopaedic Surgery at UCSF. She offers platelet-rich plasma and bone marrow aspirate concentrate as regenerative treatment options alongside arthroscopy, shoulder replacement, and fracture care at her San Jose and Campbell locations.
Address: 200 Jose Figueres Avenue, Suite 230, San Jose, CA 95116
Additional Location: 429 Llewellyn Avenue, Campbell, CA 95008
Phone: (408) 364-1673
Website: https://www.smartorthopaedicsurgery.com
Key Personnel:
- Dr. Jothi Murali-Larson, MD, Lead Physician, board-certified orthopedic surgeon, Emory University School of Medicine MD, Brown University orthopedic surgery residency, Rhode Island Hospital/Brown Alpert Medical School Orthopedic Trauma fellowship, UC Davis Health System Orthopaedic Sports Medicine fellowship, UCSF associate faculty
Services Offered:
- Platelet-Rich Plasma (PRP) therapy
- Bone Marrow Aspirate Concentrate (BMAC) therapy
- Orthobiologic injections for musculoskeletal conditions
- Arthroscopic and reconstructive shoulder and knee surgery (when indicated)
- Shoulder replacement surgery (when indicated)
- Fracture and trauma care
Conditions Treated: Knee and shoulder sports injuries, rotator cuff conditions, shoulder instability, fractures, tendon and ligament injuries, osteoarthritis, conditions requiring minimally invasive or regenerative alternatives to open surgery
Hours: Monday through Friday, 8:00 AM to 5:00 PM
4. South Bay Orthopedic and Sports Medicine
South Bay Orthopedic and Sports Medicine in San Jose is led by Dr. Samir Sharma, a board-certified orthopedic surgeon and sports medicine physician who has been in practice in San Jose for more than two decades. Dr. Sharma was raised in Michigan and pursued his undergraduate studies at the University of Miami under an honors accelerated medical program before attending Wayne State University School of Medicine in Detroit, where he graduated top of his class with highest distinction and Junior Alpha Omega Alpha honors. He completed his orthopedic surgery residency at the Detroit Medical Center, where he trained under Dr. Robert Teitge, a team physician for the Detroit Pistons. He completed a sports medicine externship at the University of Pittsburgh under sports medicine surgeons Christopher Harner and Freddie Fu, and then completed a sports medicine fellowship at Tahoe Orthopedics and Sports Medicine, during which he performed more than 400 operative cases. He is board-certified by the American Board of Orthopaedic Surgery with subspecialty certification in Sports Medicine and is affiliated with Good Samaritan Hospital and O’Connor Hospital in San Jose. The practice offers PRP therapy and advanced regenerative medicine alongside a full range of orthopedic surgical services.
Address: 333 O’Connor Drive, San Jose, CA 95128
Phone: (650) 966-7631
Website: https://www.southbayorthopedic.com
Key Personnel:
- Dr. Samir Sharma, MD, Lead Physician, dual board-certified in Orthopaedic Surgery and Sports Medicine, Wayne State University School of Medicine MD (top of class, Junior Alpha Omega Alpha), Detroit Medical Center orthopedic surgery residency, University of Pittsburgh sports medicine externship (under Harner and Fu), Tahoe Orthopedics and Sports Medicine fellowship
Services Offered:
- Platelet-Rich Plasma (PRP) therapy
- Advanced regenerative medicine for musculoskeletal conditions
- Arthroscopic sports surgery (ACL, meniscus, rotator cuff, labrum)
- Total joint reconstruction (when indicated)
- Fracture and trauma care
Conditions Treated: ACL tears, meniscal tears, rotator cuff injuries, labral tears, osteoarthritis, shoulder conditions, knee conditions, sports injuries at the high school, collegiate, and recreational level
5. Terence Delaney, MD
Dr. Terence J. Delaney is a board-certified orthopedic surgeon who has been in private practice in Los Gatos since 1993 and was among the first physicians in the greater San Jose area to offer platelet-rich plasma therapy. Dr. Delaney earned his medical degree from New York Medical College in 1986 and completed a surgical internship at St. Luke’s Hospital/Columbia University in New York. He completed a four-year orthopedic surgery residency at Catholic Medical Center in affiliation with Cornell University, where he also received training in spinal reconstruction and pediatric orthopedics at NYU/Hospital for Joint Diseases. He then completed a Joint Replacement Fellowship at Stanford University in Palo Alto. He is board-certified by the American Board of Orthopaedic Surgery and is a Fellow of the American Academy of Orthopaedic Surgeons. He has been treating patients in Los Gatos and the greater San Jose area since 1993 and is affiliated with El Camino Hospital and Good Samaritan Hospital. He is among the first orthopedic surgeons in the area to have trained in and performed PRP therapy and also performs the Oxford Unicompartmental Knee, Birmingham Hip Resurfacing, and the Biomet Signature Custom Knee Prosthesis alongside a full range of arthroscopic procedures.
Address: 14911 National Avenue, Suite 3, Los Gatos, CA 95032
Phone: (408) 356-0404
Website: https://www.terencedelaneymd.com
Key Personnel:
- Dr. Terence J. Delaney, MD, FAAOS, Lead Physician, board-certified orthopedic surgeon, New York Medical College MD (1986), Catholic Medical Center/Cornell University orthopedic surgery residency, Stanford University Joint Replacement Fellowship, private practice in Los Gatos since 1993
Services Offered:
- Platelet-Rich Plasma (PRP) therapy
- Stem cell therapy
- Joint replacement (Oxford Unicompartmental Knee, Birmingham Hip Resurfacing, custom knee prosthesis)
- Arthroscopic ACL repair, meniscus transplant, and rotator cuff repair
- Cartilage replacement procedures
Conditions Treated: Knee and hip osteoarthritis, meniscal conditions, ACL injuries, rotator cuff tears, cartilage conditions, joint conditions in patients seeking either regenerative or operative care
About This Directory
This listing is part of a national regenerative medicine directory covering major metropolitan areas across the United States. Clinics included in this directory are real, operating practices with verified addresses and publicly available contact information. Inclusion does not imply endorsement, certification, or quality rating. Patients should independently verify provider credentials, treatment protocols, and regulatory compliance before pursuing any regenerative medicine treatment.
Many regenerative medicine treatments, including stem cell therapy and PRP, are considered investigational by the FDA for most orthopedic and musculoskeletal applications. Insurance coverage for these treatments is generally not available. Patients are encouraged to discuss all treatment options, risks, benefits, and costs with their healthcare provider before making any decisions.
Last updated: March 2026