New York City is home to one of the country’s most robust concentrations of regenerative medicine providers, spanning major academic medical centers, independent orthopedic practices, and national clinic networks. Manhattan and the surrounding boroughs offer patients access to both hospital-affiliated programs at institutions such as NYU Langone and private specialty practices focused exclusively on non-surgical biologics. Whether you are managing osteoarthritis, recovering from a sports-related tendon injury, or seeking alternatives to joint replacement surgery, the providers listed below represent established practices with verified addresses, documented treatment offerings, and publicly available contact information.
This directory is for informational purposes only. It does not constitute medical advice, endorsement, or recommendation. Inclusion in this directory does not imply certification or quality rating. Always consult a qualified healthcare provider before pursuing any treatment.
Quick Guide by Condition
If you are looking for a provider based on your specific concern, this overview may help narrow your search:
Orthopedic and joint conditions (knee, hip, shoulder, spine): All six clinics listed below offer treatments for musculoskeletal pain. New York Stem Cell Therapy, Regenerative Orthopaedics, New York Bone and Joint Specialists, and NYU Langone Center for Regenerative Orthopedic Medicine focus on evidence-based orthopedic biologics using autologous methods. R3 Stem Cell uses allogeneic umbilical cord tissue.
Neurological and chronic pain conditions (neuropathy, chronic back pain, neck pain): Stem Cells Therapy NYC, led by Dr. Leon Reyfman, combines interventional pain management with regenerative therapies for chronic musculoskeletal pain.
Anti-aging and wellness: R3 Stem Cell offers exosome therapy and wellness-oriented regenerative treatments alongside its orthopedic services.
1. New York Stem Cell Therapy
New York Stem Cell Therapy is the practice of Dr. Thomas Youm, a board-certified orthopedic surgeon and Clinical Professor at the NYU School of Medicine who serves as Director of Hip Arthroscopy at NYU Langone Orthopedic Hospital. Dr. Youm completed his sports medicine fellowship at the Kerlan-Jobe Orthopaedic Clinic in Los Angeles, where he participated in the care of several professional sports organizations. His practice offers biological alternatives to surgery including bone marrow-derived and adipose-derived stem cell injections and platelet-rich plasma therapy, administered for patients seeking non-operative management of orthopedic conditions. Injections are guided by imaging and preceded by a thorough evaluation.
Address: 55 East 86th Street, Suite 1A, New York, NY 10028
Phone: (212) 348-3636
Website: https://www.newyorkstemcelltherapy.com
Key Personnel:
- Dr. Thomas Youm, MD, FACS, Founder, board-certified orthopedic surgeon, Clinical Professor at NYU School of Medicine, fellowship-trained at Kerlan-Jobe Orthopaedic Clinic, Director of Hip Arthroscopy at NYU Langone
Services Offered:
- Bone marrow-derived stem cell therapy
- Adipose-derived stem cell therapy
- Platelet-Rich Plasma (PRP) therapy
- Orthopedic biologics consultation and treatment planning
Conditions Treated: Hip labral tears, avascular necrosis of the hip, knee osteoarthritis, shoulder injuries, rotator cuff conditions, sports-related tendon and ligament injuries, degenerative joint conditions
2. Regenerative Orthopaedics
Regenerative Orthopaedics is the practice of Dr. Steven Struhl, a dual board-certified orthopedic surgeon with decades of experience treating complex orthopedic conditions. Dr. Struhl founded his regenerative practice to focus on non-surgical alternatives for patients with chronic joint pain and musculoskeletal injuries. The New York City office is located in Midtown Manhattan, with an additional location in White Plains, New York. Dr. Struhl uses stem cell therapy, PRP, and other orthobiologic treatments to address cartilage damage, tendon injuries, and arthritis, with the goal of delaying or avoiding surgical intervention.
Address: 136 East 57th Street, Suite 1501, New York, NY 10022
Phone: (212) 207-1990
Website: https://www.stemcelltherapynyc.com
Key Personnel:
- Dr. Steven Struhl, MD, Founder, dual board-certified orthopedic surgeon, member of the American Academy of Orthopaedic Surgeons and the Arthroscopy Association of North America
Services Offered:
- Stem cell therapy
- Platelet-Rich Plasma (PRP) injections
- Hyaluronic acid injections
- Traditional orthopedic injections
- Non-surgical joint preservation protocols
Conditions Treated: Knee osteoarthritis, shoulder arthritis, hip pain, ankle injuries, hand and wrist conditions, cartilage damage, tendon tears, chronic tendonitis, nonunion bone fractures
3. Stem Cells Therapy NYC
Stem Cells Therapy NYC is the practice of Dr. Leon Reyfman, a board-certified interventional pain physician who offers stem cell therapy and regenerative treatments across multiple New York City locations including Manhattan, Brooklyn, and Queens. Dr. Reyfman and his team take a minimally invasive approach to chronic pain, using the patient’s own biological material, including bone marrow-derived stem cells, to target damaged tissue at the source of pain. The practice serves patients with both acute injuries and longstanding degenerative conditions who have not found sufficient relief through conventional pain management.
Address: 240 East 23rd Street, Suite 101, New York, NY 10010
Phone: (212) 612-2222
Website: https://www.stemcellstherapynyc.com
Key Personnel:
- Dr. Leon Reyfman, MD, Founder, board-certified interventional pain physician and PRP specialist
Services Offered:
- Bone marrow-derived stem cell therapy
- Platelet-Rich Plasma (PRP) therapy
- Regenerative injections for chronic pain conditions
Conditions Treated: Shoulder arthritis, tendonitis, chronic neck pain, chronic back pain, hip arthritis, knee arthritis, ankle arthritis, chronic musculoskeletal pain conditions
4. New York Bone and Joint Specialists
New York Bone and Joint Specialists is a multi-location orthopedic practice with offices across Manhattan that incorporates regenerative orthopedic therapies into its broader non-surgical treatment program. The practice operates under the philosophy that preservation is the foundation of joint longevity, prioritizing conservative and biologic interventions before recommending surgical options. Regenerative treatments including PRP and stem cell therapies are available at all New York Bone and Joint Specialists centers and are combined with physical therapy and pain management planning when appropriate.
Address: 130 East 67th Street, New York, NY 10065
Phone: (212) 759-4553
Website: https://nyboneandjoint.com
Key Personnel:
- Multiple board-certified orthopedic surgeons and sports medicine physicians (provider names and subspecialties available on website and upon consultation)
Services Offered:
- Platelet-Rich Plasma (PRP) therapy
- Stem cell therapy
- Orthopedic injections
- Physical therapy
- Pain management planning
- Non-surgical joint preservation
Conditions Treated: Knee pain and arthritis, hip conditions, shoulder injuries, tendon and ligament damage, degenerative joint disease, sports injuries
Hours: Monday through Friday, 8:00 AM to 5:00 PM
5. R3 Stem Cell New York City
R3 Stem Cell operates a Manhattan location as part of its national network of over 45 centers across seven countries. The New York City clinic offers umbilical cord allograft tissue-based stem cell therapy, exosome therapy, and PRP treatments, with a free initial consultation available by phone or in person. R3 reports having performed over 25,000 procedures across its network. The practice positions itself as an accessible entry point for patients exploring regenerative therapies for a wide range of conditions.
Address: 22 West 48th Street, New York, NY 10036
Phone: (844) 438-7836 (844-GET-STEM)
Website: https://r3stemcell.com/nyc-new-york
Key Personnel:
- Dr. David Greene, DO, CEO of R3 Stem Cell
- Local provider staff at the Manhattan location
Services Offered:
- Umbilical cord tissue stem cell therapy
- Exosome therapy
- Platelet-Rich Plasma (PRP) injections
- Hormone replacement therapy (bioidentical hormones)
- Peptide therapy
Conditions Treated (as reported by the provider): Knee pain, hip pain, shoulder pain, back pain, neuropathy, erectile dysfunction, autoimmune conditions, COPD, neurological conditions
Insurance: Not covered
6. NYU Langone Center for Regenerative Orthopedic Medicine
The NYU Langone Center for Regenerative Orthopedic Medicine is a hospital-based program offering evidence-based biologic therapies for musculoskeletal conditions and injuries. The center’s physicians specialize in orthopedic sports medicine and use nonsurgical treatments derived from blood, proteins, and naturally occurring biological substances to reduce inflammation and support tissue healing. The center is part of NYU Langone Health, ranked among the top five hospitals in the United States for orthopedics by U.S. News and World Report. Physicians practice across Manhattan, Brooklyn, Queens, Westchester County, and Long Island.
Address: 333 East 38th Street, New York, NY 10016
Phone: (646) 929-7800
Website: https://nyulangone.org/care-services/center-for-regenerative-orthopedic-medicine
Key Personnel:
- Dr. Michael J. Alaia, MD, Sports Orthopedic Surgeon
- Dr. Laith M. Jazrawi, MD, Sports Orthopedic Surgeon
- Dr. John G. Kennedy, MD, Foot and Ankle Surgeon
- Dr. Andrew S. Rokito, MD, Shoulder and Elbow Surgeon
- Additional fellowship-trained orthopedic specialists (full roster available on website)
Services Offered:
- Platelet-Rich Plasma (PRP) therapy
- Stem cell treatments
- Hyaluronic acid joint injections
- Collagen patch applications
- Shock wave therapy
- Comprehensive non-surgical musculoskeletal care
Conditions Treated: Achilles tendon injuries, knee cartilage damage, meniscus tears, rotator cuff tears, hip labral tears, plantar fasciitis, osteoarthritis of the knee, hip, shoulder, and ankle
About This Directory
This listing is part of a national regenerative medicine directory covering major metropolitan areas across the United States. Clinics included in this directory are real, operating practices with verified addresses and publicly available contact information. Inclusion does not imply endorsement, certification, or quality rating. Patients should independently verify provider credentials, treatment protocols, and regulatory compliance before pursuing any regenerative medicine treatment.
Many regenerative medicine treatments, including stem cell therapy and PRP, are considered investigational by the FDA for most orthopedic and musculoskeletal applications. Insurance coverage for these treatments is generally not available. Patients are encouraged to discuss all treatment options, risks, benefits, and costs with their healthcare provider before making any decisions.
Last updated: March 2026