Stem Cell Therapy and Regenerative Medicine Clinics in Sacramento, CA

Sacramento’s four practices share a pattern: each is run by an orthopedic or sports physician who offers injections alongside a wider practice, rather than by a clinic that sells stem cells alone. So a Sacramento patient can ask one physician to compare surgery, PRP and marrow concentrate. Two of them are in the same suite on K Street. One is a university surgeon. One practice centers on regenerative orthopedics and works in both Sacramento and Roseville. For a joint condition, FDA has not approved any of these cell treatments.

Sacramento Practices

Clinic	Where	Physician named	What its site says it uses	Price posted
Sacramento Orthopedic Sports and Shoulder	K Street	Greg Takenishi, MD	PRP, marrow concentrate	Not posted
Hirahara MD	K Street	Alan M. Hirahara, MD	Orthobiologics, ultrasound-guided care	Not posted
Dr. Cassandra A. Lee	Alhambra Blvd	Cassandra A. Lee, MD	PRP, prolotherapy, autologous cell therapy	Not posted
The BIOS Orthopedic Institute	Fair Oaks Blvd; Roseville	Alberto J. Panero, DO	PRP, stem cell treatments	Not posted

Sacramento Orthopedic Sports and Shoulder

Dr. Takenishi says he starts “with the least invasive approach and escalating only when necessary.” His page explains PRP from your own blood and marrow concentrate, and it has a comparison of PRP with cortisone. The practice says most major insurance plans are accepted, so ask which services that covers.

• Address: 2801 K Street, Suite 330, Sacramento, CA 95816
• Phone: 916-732-3005
• Website: https://sacorthosports.com/
• Physicians: Dr. Greg Takenishi, MD
• What the site lists: PRP, bone marrow aspirate concentrate, shoulder and sports surgery
• Hours: Monday to Friday, 8am to 4:30pm
• Insurance and price: Major plans accepted for orthopedic care; injection fees are not posted on the pages read
• Ask: What would you try first if my plan will not pay for an injection?

Hirahara MD

Dr. Hirahara is an orthopaedic surgeon specializing in shoulder and knee arthroscopy and sports medicine, with a stated interest in ultrasound. His site names orthobiologics as a focus, so ask first which product he would use.

• Address: 2801 K Street, Suite 330, Sacramento, CA 95816
• Phone: (916) 732-3000
• Website: https://www.hiraharamd.com/
• Physicians: Alan M. Hirahara, MD, FRCSC
• What the site lists: Orthobiologics, shoulder and knee arthroscopy, ultrasound-guided procedures
• Insurance and price: Not posted on the pages read
• Ask: Which biologic product do you use for shoulders, and is it from me or a donor?

Dr. Cassandra A. Lee

Dr. Lee’s site lists Sacramento and Davis, and describes orthobiologics that use “substances from your own body, such as blood, platelets, or bone marrow,” along with PRP, prolotherapy, autologous cell therapy and cartilage regeneration. Her clinical interest in knee and shoulder sports injuries makes this a route for a young or active patient deciding about surgery.

• Address: 1201 Alhambra Blvd, Suite 230, Sacramento, CA 95816
• Phone: 916-734-6805
• Website: https://www.cassandraleemd.com/
• Physicians: Cassandra A. Lee, MD
• What the site lists: PRP, prolotherapy, autologous cell therapy, cartilage restoration surgery
• Insurance and price: The site has insurance pages; injection fees are not posted on the pages read
• Ask: Would cartilage repair surgery be an option for me instead, and how would the results compare?

The BIOS Orthopedic Institute

Dr. Panero’s institute describes PRP in technical terms, as platelets concentrated above normal levels in plasma, and its contact page also lists stem cell treatments. The site says these topics have been the subject of Dr. Panero’s conference presentations. Ask which of the two it would use for you.

• Address: 2277 Fair Oaks Blvd, Suite 415, Sacramento, CA 95825; also 576 N. Sunrise Ave, Suite 130, Roseville, CA 95661
• Phone: 916-418-4442
• Website: https://thebiosinstitute.com/
• Physicians: Alberto J. Panero, D.O.
• What the site lists: PRP, stem cell treatments, regenerative orthopedics, sports medicine
• Insurance and price: Not posted on the pages read
• Ask: What platelet concentration do you target for my problem, and how do you confirm it?

California Board and Notice Questions

The Medical Board of California licenses these physicians. California’s section 684 requires a posted notice for covered stem cell therapy not approved by FDA, and it defines that therapy by reference to human cell and tissue products. FDA’s guidance says PRP is not one, so a PRP-only office may post nothing; ask if you are unsure which you are getting. The same section also calls for the medical board to report annually on licensees providing stem cell therapies. The linked copy is dated 2019, so check the current text.

FDA and Evidence for Sacramento Patients

FDA’s consumer notice says regenerative therapies have not been approved for any orthopedic condition, even when cells come from your own body. Its guidance keeps marrow outside its tissue rules only when minimally manipulated and used for its normal function.

A randomized trial of 480 knee patients (440 analyzed) found marrow, fat and cord tissue cells no better than cortisone at one year. The American College of Rheumatology’s 2026 recommendations strongly recommend against PRP and stem cell injections in the knee and hip, while the American Academy of Orthopaedic Surgeons’ 2021 guideline rates PRP “Limited.” Patients who can reach the Bay Area can also see the San Francisco list.

Practice details are as we found them on each website in November 2026, and it is worth confirming them by phone. This page is not a recommendation or ranking, and your own physician should guide your care. FDA has received reports of blindness, tumors and infections from unapproved regenerative products.